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雷公藤多甙治疗20例原发性肾病综合征的近期疗效观察
多年来雷公藤多甙的应用一直沿袭常规剂量(1mg*kg-1*d-1),但作用缓慢,不如激素快捷,即使微小病变型肾病综合征也常常首选激素,雷公藤多甙只是作为维持阶段的辅助性治疗[1].我科应用双倍剂量雷公藤多甙(2mg*kg-1*d-1),观察了20例原发性肾病综合征的近期疗效和副反应,报道如下.
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参附注射液与维生素C治疗急性病毒性心肌炎的临床疗效观察
病毒性心肌炎是心血管内科常见病,近年来发病有逐年增多趋势,由于其发病机理尚不十分明确,多年来一直无特效治疗方法,一般采用休息和对症治疗等,疗效难以使人满意.本研究采用参附注射液与维生素C注射液对比治疗急性病毒性心肌炎,现报告如下.资料与方法1 观察对象 60例均系本院住院及心血管专科门诊患者,均符合1987年中华内科杂志编委会全国心肌炎心肌病专题座谈会制定的成人急性病毒性心肌炎诊断参考标准(1),近1~2周患上呼吸道感染,自觉心累、心悸、胸闷等.随机(用信封法)分成2组,参附组30例,男21例,女9例,年龄21~46岁,平均(34.0±5.8)岁,病程平均(7.3±3.4)天;心电图有改变者(ST段压低或T波低平)28例,其中室性早搏者8例.维生素C组30例,男20例,女10例,年龄21~42岁,平均(32.7±5.4)岁,病程平均(8.1±2.8)天;心电图有改变者26例,其中室性早搏者6例.两组年龄、性别、病程、心电图改变等比较差异无显著性.2 治疗方法参附组采用参附注射液(雅安三九药业公司生产,批号9921201,每毫升含生药红参0.1g,附子0.1g)60ml加5%葡萄糖注射液150ml静脉滴注,每分钟15~20滴,每天1次,连续用药10天.维生素C组每天静脉滴注5%葡萄糖注射液150ml加维生素C 3g,连续10天.两组患者均适当休息,除有心律失常者适当加用阿替洛尔、慢心律或心律平等对症治疗外,无其他特殊治疗.观察用药前后症状体征、心肌酶学(用速率法)、心电图指标及不良反应.3 统计学处理两组临床疗效和心电图疗效比较采用χ2检验,心肌酶学指标比较采用t检验.
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Objective: To evaluate the therapeutic effect of Chinese patent drug Shu Feng Huo Luo Pian (疏风活络片 Pill for Dispelling Wind and Activating Collaterals) for the treatment of osseous arthritis. Method: 50 cases of osseous arthritis were divided randomly into two groups, the Shu Feng Huo Luo Pian group (the experimental group), including 30 cases (aged 63.5±4 years), treated with 2 such pills, po, bid; and the control group, including 19 cases (aged 63±5 years), treated with Sulindac 0.2g, po, bid. The two groups were all supplemented by medication of calcium Caltrate D 0.6g, po, qd. The above-mentioned medications were administered for 2 courses, 2 weeks constituting a course. Result: The total effective rate of the experimental group evaluated by the doctors was 83.3%, and that evaluated by the patients was 90%, with mild side effects. Conclusion: Shu Feng Huo Luo Pian is an effective Chinese patent drug for treating osseous arthritis, with less and mild side effects. Osseous arthritis is characterized mainly by chronic arthralgia, ankylosis, and arthroncus accompanied with dysfunction of the joint. It affects predominantly the movable joints of the human body, such as the joint of the hip, knee, ankle, elbow, and finger. It is a commonly seen disease, which mostly affects the life activities of the aged people. Its morbidity rises along with age. X-ray mass survey has shown that the morbidity of this disease among people aged 15-24 years is about 10%, while that among people aged 55 years is about 80%1. As China is entering an aged society, due attention should be paid to this kind of disease. This article offers a clinical observation on the therapeutic effect of Shu Feng Huo Luo Pian (疏风活络片 Pill for Dispelling Wind and Activating Collaterals) for 50 cases of osseous arthritis as reported below.
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青海地区老年人心力衰竭患者血浆BNP水平变化与临床观察分析
心力衰竭(HF)是导致大多数心血管疾病的主要因素,近10年死亡率为90%~([1]).而青海地区平均海拔在3 000 m以上,具低氧、气候寒冷干燥的特点,老年人在此环境中易造成血管收缩,代谢异常,机体抵抗力降低,容易诱发HF.
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中药内服外用治疗勃起功能障碍(ED)50例临床观察
从2003年3月~2005年3月笔者采用中药内服外用治疗勃起功能障碍(ED)50例,治疗前后应用阴茎勃起角度值的对比进行疗效评估,疗效满意,报告如下.
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腰椎间盘突出症术后早期主动训练效果的临床观察
Objective To explore the recent and distant effects of early active training after the operation for lumber intervertebral disc herniation.Method 79 patients after the operation for mono segmental lumber intervertebral disc herniation had been divided into early active training group and routine control group randomly, and accepted training, regular re examination, and follow up of 1~ 6 years respedtively.Results The early active training group had better recent and distant objective effect, and more patients (97.6% ) were satisfied with the operational effects.Conclusions The early active training after the operation for lumber intervertebral disc herniation is positive significant for operational effects.
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改良腭弓矫治后牙锁节对后牙功能恢复的影响
Background: Buccal teeth occlusion lock is a kind of common malocclusion malformation in orthodonic clinic. Traditional treatment to buccal teeth occlusion lock is interactive traction of upper and lower buccal teeth.This treatment had shortcoming such as insufficient anchorage and elongation of buccal teeth.We adopted promote fix palatine arch therapy, which recovery patients' occlusion function by clinical observation.
关键词: 腭弓 矫治 后牙 功能恢复 Clinical Observation -
硫酸吗啡控释片治疗重度癌痛剂量个体化的疗效观察
Morphine is classical analgesic with strong effect. Nowadays, controlled- release morphine tablets(MS Contin) are the most advanced among all morphine forms, which has been widely used clinically. Thirty advanced cancerous patients with severe pain were treated with MS Contin from March 1995 to December 1997. The following is the report of clinical observation. 1 Subjects and methods 1.1 Subjects Thirty patients of advanced stage (M,18, F,12 ;age:52± 13years) except primary hepatocarcinomas had pathological or cellular proof . There were 7 cases with hepatocarcinoma, 6 cases with lung cancer, 4 cases with breast cancer , 3 cases with gastric carcinoma, 2 cases with mutiple myeloma, 2 cases with colon cancer and 1 case with pancreatic carcinoma. These patients did not take adrenocortical hormones, sedative, soporific, antidepressants, antihistamines and were not treated with chemotherapy and radiotherapy . 1.2 Methods The grades of pain use VRS. 0 grade: Patients feel no pain.1st grade: Patients feel light pain and can live normally. Their sleep is not disturbed. 2nd grade: Patients feel obvious pain and cannot bear and require taking analgesic. Their sleep is disturbed. 3rd grade: Patients feel severe pain and cannot bear and need to take analgesic. Their sleep is seriously disturbed. All cases were treated with MS Contin tablets(30mg,q12h,po).If there were no obvious effect, doses of 30 mg were added every time. The maximum dose per time was 120 mg .When the doses could make them achieve obvious effect, the patients were treated for over 3 days. All tablets were swallowed and were not chewed.
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CT环池改变及脑干听觉诱发电位对重型颅脑外伤患者观察病情及判断预后的价值
重型颅脑外伤患者的死亡率、致残率高,早期诊断和治疗可降低死亡率、致残率.本研究探讨CT环池影像及听觉诱发电位(BAEP)对判断重型颅脑外伤患者病情及预后的价值.
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高原小儿外科感染性休克探讨
本文对105例高原小儿外科感染性休克进行了总结.临床观察和实验室资料表明,高原地区健康小儿的血液流态具有粘、浓、聚三大特点,微血管在缺氧环境下处于痉挛代偿状态.感染性休克时血管痉挛明显加重,持续时间长,代偿机能差,休克早期就会出现微循环障碍,因而高原小儿感染性休克具有发病急、进展快,病情重、病死率高等临床特点.早期诊断、早期治疗对于提高抢救成功率,降低病死率有重要意义.
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小儿皮下感染局部免疫的临床观察
本文利用大量的临床资料分析了不同年龄组之间,同一年龄组不同患儿之间,同一机体不同部位,以及同一感染的不同阶段对感染的免疫反应的不同表现,从病理和免疫发生等方面提出了新的假说,对临康治疗有一定指导意义.
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小儿感染、免疫与多器官衰竭
小儿体表软组织非特异性化脓性感染,是小儿外科的常见病.严重者可引起多系统器官功能衰竭而致死亡.
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灭滴灵直肠栓剂预防小儿阑尾切除术后切口感染的疗效观察
我院自1983年12月开始对小儿急性阑尾炎术前加用灭滴灵直肠栓剂预防切口感染,现将其疗效报道如下:临床资料以1983年12月~1984年12月我院收治的小儿急性阑尾炎切除术66例为灭滴灵组,所有患儿术前0.5~1小时常规应用灭滴灵直肠栓剂0.5~1.0g,其中剔除经原切口烟卷引流和二期缝合切口者4例,余62例.
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血定安用于术中低血容量的临床观察
血定安是新一代明胶改良配制的血浆代用品.通过对30例成人腹部手术患者不输血而输注血安定以观察其血液动力学和血系生化的变化.
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湿性脂肪干细胞辅助自体颗粒脂肪移植术研究进展
近年来,自体颗粒脂肪(adipose granule,AG)、脂肪干细胞(adipose derived stem cells,ADSCs)[1]、ADSCs辅助AG注射填充移植术(cell-assisted lipotransfer,CAL)[2]、血管基质细胞(stromal vascular fraction,SVF)[3]、新鲜SVF辅助AG移植术[4]等热点研究,基本突破了严重制约临床传统单纯多量大体积AG注射填充移植术吸收率高[5-6]的瓶颈难题,为多量大体积AG注射填充移植在整形美容领域带来新希望;2008年,刘乃军针对CAL技术客观公正地创造性定义和分类为干性CAL和湿性CAL概念,对规范湿性CAL临床标准流程具有重要意义[7],并采用湿性CAL技术成功进行了多量大体积AG注射填充移植临床应用及远期随访观察研究[8],与5年前同等条件下采用传统单纯湿性AG注射填充移植所完成的远期随访结果相比[9],取得了良好和稳定的预期临床效果,目前临床上仍以湿性CAL应用广泛.现将湿性CAL实验和临床新研究心得综述如下.