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The aim of this study is to investigate the effect of electro-acupuncture treatment in acute phase of cerebral infarction on the motor functions. In this randomly controlled trial, 86 patients were allocated to two groups, the experimental group given clinical and electro-acupuncture treatments for a period of 4 weeks, and the control group given clinical treatment plus active and/or passive functional exercise. The result showed that the level of impairment and disability in both groups were improvement according to the Chinese Stroke Scale, Brunnstrom-Fugl-Meyer score, and Barthel Index throughout the study and 3 months after. The motor functions and the activities of daily living (ADL) were improved significantly in the electro-acupuncture group as compared with the control group (P<0.05). Also, the results showed greater reduction of neurological deficit in the electro-acupuncture group than in the control group. Conclusion: Early acupuncture treatment for acute stroke patients may improve motor functions, and consequently the activities of daily living.
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不同亚型α干扰素抗病毒作用研究进展
I 型干扰素( IFN)是病毒感染后宿主体内产生的一类多功能细胞因子,它们属于多基因家族,到目前为止,已发现7种I型IFN 即IFN-α、β、ε、κ、ω、δ、τ,具体的分型原因不清楚,推测可能是各型IFN性能不同或者各型IFN产生的时间顺序和细胞种类不同。 IFN-α因具有多种生物学效应而被广泛应用,医学上常用外源性IFN-α进行抗病毒、抗肿瘤、抗增殖等治疗,其中尤以抗病毒治疗为重要。 IFN-α包括多种亚型,文献报道各种亚型的抗病毒作用具有亚型和病毒特异性,但是其详细机制尚未完全明了。本文仅就不同亚型IFN-α抗病毒作用的研究现状进行综述。
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重视静脉疾病的临床治疗及基础研究
静脉疾病是血管外科疾病的重要组成部分,其在人群中的总体发病率和疾病复杂程度都要超过动脉疾病.统计资料表明,静脉血栓栓塞症在美国的发病率为77.6/10万人,每年新发病例有275 000例之多.
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树突状细胞疫苗在肿瘤临床治疗中的应用
树突状细胞(Dendritic cell,DC)是目前发现的功能强大的抗原提呈细胞,其功能独特之处在于能捕获、提呈肿瘤抗原并激活初始型T细胞,从而引发一系列的肿瘤抗原特异性的免疫应答。
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带蒂部分尺侧屈腕肌转位重建尺侧副韧带治疗桡尺远侧关节脱位
Background:For the clinical treatment of dislocation of distal radioulnar articulation, removal of smaller head of ulna was often adopted .Because this operation damaged ulnar stabilization of wrist, therapeutic effect couldn't be sustained for a long time, even semiluxation of carpal bone appeared.
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不同术式治疗腰椎管肿瘤合并腰椎间盘突出患者疼痛的疗效观察
Background: There was seldom report on lumbar spine tube tumor combined with prolapse of lumbar intervertebral disc. In clinical treatment doctors are usually satisfied by the discovery of prolapse of lumbar intervertebral disc, and neglect the existence of tumor. The main symptoms are lumbago, and its obviously when patients rest at night. Objective: To explore curative effects of different therapies to treat patients' pains of lumbar spine tube tumor combined with prolapse of lumbar intervertebral disc. Unit: People Hospital of Taizhou City.
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咳嗽从瘀血论治经验
咳嗽是肺系疾患的一个常见证候,引起咳嗽的原因很多,有外感咳嗽和内伤咳嗽之分,多数医家多责之于肺、脾、肝、肾之病变所致,或因感受风、寒、热、燥、火之邪而发,或因脾虚生痰、肝火犯肺、肾气虚衰等导致。近年来研究发现,瘀血是导致咳嗽的重要病因之一,尤其是见于久病顽疾咳嗽患者。我们临床治疗慢性支气管炎、哮喘、肺心病、支气管扩张等患者之咳嗽,每以瘀血论治,常获佳效。现就瘀血咳嗽的论治经验简述如下。
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积极抗高血压治疗与临床获益——降压幅度和速度思考
高血压是心血管系统的常见疾病,是导致心脑血管损害和事件的重要危险因素之一,其患病率逐年增加;据2006年中国心血管病报告估算,高血压罹患人数已达2亿.经历了半个多世纪,高血压防治取得了巨大的成就,就血压治疗的观念亦发生了重大的转变.从初阶段以控制血压、降压达标为主;到以后以控制血压、大限度减少心脑血管事件.
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HIV耐药性研究进展及其临床应用前景
1 前言自从叠氮胸苷作为有效的抗艾滋病病毒(HIV-1)问世以来[1],抗病毒治疗已经广泛地应用于发达国家艾滋病病毒感染者的临床管理中.临床实践表明:抗反转录(RT)酶和抗蛋白酶抑制剂(PI)的联合使用,有效地降低了感染者血浆中HIV的水平、推迟HIV感染的临床进程,大大地降低了与HIV/AIDS相关的发病率和死亡率[2].但是由于对抗病毒药物耐受而导致治疗失败已经引起药品开发、临床管理和公共卫生等部门的关注.不少文献报道:近年来,HIV耐药性的传播呈上升趋势,多重耐药明显增加[3~5].现将HIV耐药性研究进展及其临床应用前景综述如下.
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未足月胎膜早破的临床治疗研究进展
未足月胎膜早破(preterm premature rupture of membranes,PPROM)是产科常见的并发症,其临床治疗方法有预防性治疗、期待疗法和适时适式终止妊娠.PPROM的治疗方法及时机至关重要,否则将会导致严重的母儿并发症,因而,选择正确的个体化治疗方法及时机对于改善PPROM患者的母儿预后非常重要.
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胰腺假性囊肿的分类及临床治疗
假性胰腺囊肿(Pancereatic pseudocyst,PPC)是临床常见疾病,多继发于急、慢性胰腺炎、胰腺手术后或胰腺外伤所致的胰液外渗或胰管断裂所形成的局部包裹性囊肿,亦有少数患者继发于恶性肿瘤或无明显原因.传统的治疗方法是通过手术治疗,但是近年来,随着微创技术、内镜技术的发展.使得PPC的治疗手段更加丰富.
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案说实验性临床医疗
在开展实验性临床医疗过程中产生诉讼怎么办?是抱怨医学的残酷还是法律的无情?
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加强病区药品贮存管理,确保临床用药安全有效
病区药柜是设在病区的一个临时小药房,用于存放少量急救药品和部分常用药品,各病区都根据各自的专业特点贮存了一些不同种类的药品包括抢救用药、毒性药品、麻醉药品及少量患者临时使用的常用普通药品[1],是临床药品供应不可缺少的一种补充方式.其主要功能是为救治危重患者赢得宝贵时间,在病人病情突变时保证临时医嘱可以得到及时有效的执行[2].病区药品管理工作由病区护理人员来执行操作,但许多临床科室在实际工作中对药品管理存在认识不足、管理不严、管理不规范等情况,而病区药品管理的好坏,会直接影响到患者用药的安全性.
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骰骨骨折的临床研究进展
骰骨作为足的重要组成部分,对于足结构、功能的完整有重要的意义和作用.骰骨骨折在临床上较少见,且容易被忽视,所以骰骨骨折的治疗方法目前尚无统一观点.近年来,越来越多的专家学者开始对骰骨骨折进行基础和临床研究,对骰骨骨折的认识也日趋成熟.
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Objective: To determine the efficacy and safety of early intervention with nimodipine treatment in diffuse axonal injury.Methods: Based on the characteristic radiological signs and criteria for diffuse axonal injury (DAI), 89patients with the diagnosis of DAI were enrolled in this randomized, double-blind, placebo-controlled trial. Results: Nimodipine proved to be safe and well tolerated. With TCD sonography we found that there was a higher incidence of cerebral vasospasm in this series (38.2%). Overall, Nimodipine produced a better clinical result than placebo, but there was no statistically significant difference in favorable outcome at 3 months after injury (P = 0.11 ) between the two groups. A trend toward a favorable effect was suggested by the analyses in two small subgroups, either in the patients suffering from clinical Grade Ⅲ DAI (P = 0.04), or in those with the TCDevidence of cerebral vasospasm during clinical observation (P = 0.049).Conclusions: We postulate that a clinically valuable benefit is possible with nimodipine treatment in DAI patients. However, the effects on outcome should be verified by further controlled study.
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Atotal of 62 papers have been published in the Chinese Journal of Traumatology (E nglish Edition) (CJT), covering scope of both basic scientific and clin ical study of traffic, craniocerebral, thoracic, extremity, spi nal and spinal cord injuries. Most of them have revealed the latest findings of basic scientific research or clinical treatment on traumatology in China, which, at the same time, play an indispensable role in communication with the foreign researchers.