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Effect of relaxation on the level of nursing internship students' stress
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142例危重病人应激性溃疡出血防治观察
应激性溃疡(stress ulcer SU),亦称为急性胃黏膜病变.是指机体在各类严重创伤、危重疾病或严重心理应激状态下所引起的食管、胃或十二指肠等部位急性糜烂、溃疡.主要表现为上消化道出血[1].
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压力性尿失禁的手术治疗
女性压力性尿失禁(stress urinary incontinence,SUI)的标准术式是阴道无张力尿道中段悬吊带术和以Bureh为代表的耻骨后膀胱颈悬吊术.使用合成材料医用材料的阴道无张力尿道中段悬吊带术因其更微创和易于操作,目前已成为全球一线的抗尿失禁的手术治疗方法.
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女性盆底功能障碍性疾病非手术治疗进展
女性盆底功能障碍性疾病(pelvic floor dysfunctional disease,PFD)主要包括盆腔脏器脱垂(pelvic organ prolapse, POP)和压力性尿失禁 (stress urinary incontinenee,SUI).近年来,女性盆底功能障碍性疾病的手术治疗已取得巨大的进步,许多手术具有微创、疗效好、住院时间短等优点,但手术治疗多针对于重度的患者,对于轻度患者,则多主张采用非手术治疗.
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高同型半胱氨酸血症导致血管内皮细胞功能损伤机制的研究进展
高同型半胱氨酸血症(hyperhomocysteinemia, Hhcy)作为心血管疾病的独立危险因素的认识已经达到分子水平.国内外大量的研究已经证明Hhcy可能通过多种机制引起血管内皮细胞(vascular endothelial cell, VEC)功能损伤,主要的通过氧化应激(oxidative stress, OS)机制导致一氧化氮(nitrogen monoxidum, NO)浓度降低及功能减退,同时通过内质网应激(endoplasmic reticulum stress, ERS)机制诱导细胞凋亡(programmed cell death, PCD)、未折叠蛋白反应(unfolded protein response, UPR)、影响脂质代谢、促进炎性介质释放等其它机制终导致VEC功能损伤.
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经闭孔无张力吊带尿道中段悬吊术治疗女性压力性尿失禁
压力性尿失禁(stress urinary incontinense,SUI)是中老年妇女的常见病,严重影响患者的生活质量,治疗SUI的手术方法很多,1914年How-ard Kelly提出了阴道前壁修补术,并用此种手术方式治疗SUI.此后治疗SUI的手术方式不断改进并发展,近10年来无张力吊带技术广泛应用于SUI的治疗,并取得了较为肯定的疗效.吊带手术根据手术路径的不同分为耻骨后路径的尿道中段悬吊术和闭孔路径的尿道中段悬吊术.经典的无张力吊带手术是通过耻骨后途径穿刺并悬吊尿道,常出现膀胱损伤等并发症,术中需行膀胱镜检查,术者需同时具有膀胱镜检查的设备及技术.
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危重症患者应用奥美拉唑预防应激性溃疡的疗效分析
应激性溃疡(stress ulcer,SU)是指机体在各类严重创伤、危重疾病等严重应激状态下,发生的急性消化道糜烂、溃疡等病变,后可导致消化道出血、穿孔,并使原有病变恶化的急性致死性并发症.
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Advances in Research of Nesfatin-1Mediated Stress and Stress-Related Anxiety and Depressive Disorder
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珠江三角洲交通伤患者创伤后应激障碍分析
创伤后应激障碍(post-traumatic stress djsorder,PTSD)是指突发性、威胁性或灾难性牛活事件,如灾害、战争、恐怖事件、事故、虐待等引起的巨大痛苦或受惊吓、遭遇悲剧导致个体长期持续存在的精神障碍[1,2].道路交通事故(road traffic accidents,RTA)是现代社会常见创伤性事件,也是导致PPSD的常见因素之一[3].
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氧化应激与新生儿脑损伤
新生儿脑损伤是围生期严重的并发症,常见的损伤类型为新生儿缺氧缺血性脑病(HIE)、新生儿颅内出血及早产儿脑白质病变,其发病机制极为复杂.在正常情况下,体内自由基的产生和清除是平衡的,当自由基产生过多或体内抗氧化系统功能障碍,自由基蓄积过多,攻击机体,即为氧化应激(oxidative stress).新生儿大脑对氧化应激特别敏感,常导致严重的脑组织损伤,已引起人们越来越多的重视.
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Oral administration of hyperoxygenated solution for the prophylaxis of gastric ulceration induced by stress or Helicobacter pylori
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Objective: To explore the effect of different anesthesia and analgesia methods on the T lymphocyte subsets, cytokines and the levels of the stress hormone in patients with breast cancer surgery.Methods: 86 cases of breast cancer were divided into two groups by random digits table, control group of 43 cases with total intravenous anesthesia, and the observation group of 43 cases with total intravenous anesthesia combined with epidural anesthesia and postoperative underwent analgesia. The T lymphocyte subsets, cytokines and the levels of the stress hormone were detected before and after operation and compared. Results:CD3+, CD4+ and CD4+/CD8+ of the two groups at T1 or T2 were significantly lower than those at T0, and those in the observation group were significantly lower than the control group, and the difference between the two groups has statistical significance. IL-6, CRP and TNF-α levels of the two groups at T1, T2 or T3 were significantly higher than those at T0, and those in the observation group were significantly lower than the control group, and the difference between the two groups has statistical significance. Each index of two groups at T4 were restored to T0, and the differences were no statistically significant. The cortisol levels of two groups at T1 or T2 were significantly increased compared with T0, and the increase in the observation group was less than that of the control group, the difference between the two groups has statistical significance. The cortisol levels of two groups at T4 were restored to T0, and the differences were no statistically significant.Conclusion:Epidural analgesia after the intravenous anesthesia combined with epidural anesthesia for breast cancer cure patients has lighter immunosuppression and stress reaction, has less influence on inflammatory factors, is an ideal anesthesia and analgesia.