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Objective:In order to obtain the data for diet and physical exercise, we analyzed the rules and characteristics of somatotype distribution of college students in Cangzhou by Heath-carter method. Methods:332 college students (172 males and 160 females) of Han nationality aged 19 to 24 were somatotyped by Health-carter anthropometry. Every index was measured 3 times and average values were adopted, and compared to that of other regions. Results:①The mean somatotype for female was 4. 3-3. 6-2. 9. The values of HWR, SAM, BMI and the rate of body fat were 42. 9, 2. 0, 20. 6 and 19. 7%, respectively. The mean somatotype for male was 3. 8-4. 3-3. 3. The values of HWR, SAM, BMI and the rate of body fat were 43. 5, 2. 4, 21. 5 and 17. 7%, respectively. The significant sexual difference was found in somatotype of Han nationality college students (P<0. 01). ②The weight, height, perimeter of the upper arm, calf girth, biepicondylar breadth of the humerus and biepicondylar breadth of the femur of male samples were greater than the female samples, the skinfold of the male samples were thinner than the male samples ( P<0 . 05 ) . ③The somatotypes of Han nationality in Changzhou were closer to the Han nationali-ty in Shandong province, but the gap was larger with Manchu and Mongolian nationality. ④Compared with foreign female college students, except Czechoslovakia and Canada, the somatotypes of Han nationality in Changzhou were similar to other countries. Conclusions:①The characteristics of male showed less body fat, stronger skeletal mus-cles, while that of female showed more body fat. ②Compared with other groups, it showed that somatotypes may be related to innate genetic, geographical climate, lifestyle, eating habits and other factors.
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构建活体中国汉族成人脑内结构正常参考值数据库的研究概述
[编者按]本期重点号为中国汉族正常成人数字标准脑研究,重点报道了脑内多个重要结构的MRI测量结果,对促进脑疾病和功能的研究具有重要意义.该研究为多中心研究,资料数据来源于全国18所大学附属医院,然后将所有资料汇总于同一个数据库,后再从数据库中提取数据对脑内的各个部位进行测量.
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重视中国汉族正常成人数字标准脑的研究
脑是人体重要的器官,研究正常和病理状态下人脑结构和功能是当今科学界的重大课题,而这些研究通常将脑功能信息标记到标准脑结构之中,这对从整体水平探索意识起源的奥秘和脑疾病的发生机制,从系统水平研究、认识、保护和开发脑功能均具有重要意义.
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Objective. To study the associations of IDDM3, IDDM4, IDDM5 and IDDM8 with insulin-dependent diabetes mellitus (IDDM). Methods. The polymorphisms of short tandem repeat (STR) loci D15S657, D11S1369, D6S2420 and D6S503, linked to IDDM3, IDDM4, IDDM5 and IDDM8 respectively, were studied by polymerase chain reaction and polyacrylamide gel electrophoresis (PCR-PAGE) followed by direct sequencing of PCR products in 105 normal Chinese Han nationality subjects and 48 patients with IDDM. Results. The allele frequencies of allele A5 at D15S657 locus, allele A5 at D11S1369 locus and allele A4 at D6S2420 locus were increased significantly in patients with IDDM compared to those in the control group. No difference in the allele frequencies at D6S503 locus was observed between IDDM and control group. Conclusion. IDDM3, IDDM4 , IDDM5 but not IDDM8 may be associated with IDDM in Chinese Han nationality population.
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Toll-样受体4基因单核苷酸多态性与中国汉族患者脓毒症的相关性
Objective To investigate the correlation between Toll-like receptor 4 (TLR4) single nucleotide polymorphism (SNP) and the risk,severity and prognosis of sepsis in Chinese patients of Han nationality.Methods One hundred and three Han nationality patients who developed sepsis after surgery,aged 18-80 years,were enrolled in the sepsis group,and 114 Han nationality patients without sepsis after surgery,aged 18-80 years,were enrolled in the control group.Venous blood samples were taken from the peripheral vein and three SNPs in TLR4 gene,rs10759932,rs11536889 and rs2737190,were genotyped by matrix-assisted laser desorption ionization time of flight mass spectrometry analysis.Correction for Logistic regression analysis was made to eliminate the effects of sex,age,underlying diseases and operation methods.The correlation between genotypes of SNP and occurrence of sepsis,organ dysfunction,septic shock and death from sepsis was analyzed.The odds ratio (OR) and 95% confidence interval (Cl) were calculated.Results Compared with the control group,there was a significant difference in genotype frequency ratios of rs10759932 (P < 0.05),but there was no significant difference in genotype frequency ratios of the other two SNPs in sepsis group (P > 0.05).There was correlation between rs10759932 and the occurrence of sepsis,and the variant allele (CT + CC genotypes) of rs10759932 increased the risk of sepsis (OR =1.86,95% Cl 1.17-2.97,P < 0.05).There was no correlation between the three SNPs and sepsis-related organ dysfunction,septic shock and death from sepsis (P > 0.05).Conclusion There is correlation between the variant allele of TLR4 rs10759932 and the increase in risk of sepsis after surgery in Chinese patients of Han nationality.
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新疆维吾尔族和汉族冠心病病人生活质量现状及影响因素分析
心血管疾病是严重危害人类健康的疾病.由于人口老龄化、社会竞争日趋激烈、饮食习惯不良及结构不合理、生活节奏加快等因素的影响,心血管疾病的发病率有逐年增高的趋势.据2007年中国卫生部新流行病学调查显示心血管疾病仅次于恶性肿瘤,高居疾病死亡率第2位,其中冠心病占心血管疾病死亡率67.1%,冠心病已经成为危害我国人民健康和增加社会经济负担的主要疾病之一.
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汉族与蒙古族大学生父母养育方式比较研究
国内外学者对父母养育方式与子女人格发展以及心理健康的关系进行了大量研究,显示:父母的养育方式对子女的成长至关重要,不当的教育方式易使子女罹患神经症或形成不良的性格[1-4].
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中国西北地区汉族家族性IgA肾病发病及临床特点
IgA肾病(IgAN)是常见的肾小球疾病,越来越多的学者发现IgAN具有一定的家族聚集性,提示IgAN可能与遗传有关.我们收集了我院西北地区汉族的IgAN患者的临床资料,对家族性IgAN(FIgAN)在西北地区汉族的发病情况、临床特点进行了分析.
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人类白细胞抗原Ⅱ类基因与天津汉族2型糖尿病肾病的相关性研究
人类白细胞抗原(HIJA)基因型是迄今为止所知复杂的遗传多态系统,目前l型糖尿病与HIJA-DQA1的关系已比较明确.近年研究显示,2型糖尿病(T2DM)与HLA也存在着一定的关联.本研究应用基因芯片技术检测HLA一Ⅱ类基因,探讨其与T2DM及糖尿病肾病(DN)的相关性.
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内蒙古汉族IgA肾病临床病理与肿瘤坏死因子β基因多态性的关系
IgA肾病(IgAN)是一种多基因病,其发病可能与HLA连锁的某些基因(HLA-DR4、A、B、DQ)有关[1].肿瘤坏死因子(TNF)位于HLA-Ⅲ抗原基因簇内,因此TNF基因可能是IgA肾病的易感基因.本研究分析IgA肾病患者临床特征与TNF-β基因多态性的关系,了解内蒙古地区汉族TNF-β基因多态性与IgA肾病各种病理类型的关系.
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Objective To determine the allelic frequency distribution and genetic parameters of nine non-CODIS DNA index systems of the short tandemrepeat (STR ) loci (D2S1772, D6S1043, D7S3048, D8S1132, D11S2368, D12S391, D13S325, D18S1364, and GATA198B05). Methods A total of 353 blood samples were collected, extracted, amplified, and analyzed fromunrelated healthy individuals of Han na-tionality in Hunan Province, China. Results O ne hundred and fourteen alleles were observed in the pop-ulation with corresponding allelic frequencies ranged from0.001 0 to 0.323 0. For all the nine non-CODIS STR loci, the observed genotypic data showed no significant deviations fromthe Hardy-W einberg equi-librium. The Ho, He, PIC, D P, and PE of the studied non-CODIS STR loci ranged from0.108 0 to 0.195 0, 0.805 0 to 0.892 0, 0.770 0 to 0.860 0, 0.925 0 to 0.966 0 and 0.607 0 to 0.780 0, respectively. Conclusion N ine non-CODIS STR loci have high degrees of polymorphisms, which may be useful in in-dividual forensic identification and parentage testing in forensic practice.
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Long-Term Trend of Bone Development in the Contemporary Teenagers of Chinese Han Nationality
Objective To further improve the accuracy of bone age identification using the time of secondary ossification center appearance and epiphyseal fusion of 7 joints to estimate the age of living individuals.Methods DR films were taken from 7 parts including sternal end of clavical and the left side of shoulder,elbow,carpal,hip,knee and ankle joints of 1709 individuals who came from eastern China,central China and southern China,whose ages were between 11.0 and 20.0 years.From those 7 joints 24 osteal loci were selected as bone age indexes,which could better reflect age growth of teenagers.The characteristics of secondary ossification center appearance and epiphyseal fusion were observed,and the mean and age range of secondary ossification center appearance and epiphyseal fusion were calculated.Results The fusion time of the 24 epiphyses were advanced at different degrees,the most obvious epiphyses the sternal end of clavicle,scapular acromial end,distal end of the radius,distal end of the ulna,iliac crest,ischial tuberosity,the upper and lower end of tibia and fibula.The appearance time of sternal end of clavicle,scapular acromial end,iliac crest and ischial tuberosity epiphyses were all found to be after the age of 12,and the female's age,approximately 1year ahead of schedule in comparison with the male's.Conclusion The relevant forensic information and data for bone age identification should be updated every 10-15 years so as to provide accurate and objective evidence for court testimony,conviction and sentencing.