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长期使用呼吸机病人停机时的护理
呼吸机主要用于各种原因引起的急、慢性呼吸衰竭或呼吸功能不全症.原发疾病对机体的损害加之手术创伤时机体产生的应激反应,不少病人在术后由于各种原因并发呼吸功能衰竭而使用呼吸机辅助呼吸维持生命,渡过疾病的危重期.我院ICU病区在2001年1月-2004年10月共收治使用呼吸机病人46例,临床护理发现短时间使用呼吸机辅助呼吸的病人,呼吸功能恢复后能很快停机.但使用呼吸机较长时间的病人,一般为两周以上者,就会对呼吸机产生较强的依赖性,需要一个逐步撤机的过程,同时需要护理人员把握好停机的原则,更要做好病人的思想工作,解除病人的心理负担,取得病人的配合,循序渐进,才能取得满意的疗效,现主要介绍长期使用呼吸机病人停机时的护理体会.
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烧伤湿润膏与青霉素粉治疗压疮临床效果
BACKGROUND:Patients resting in bed often presented with bed sore which etiology was blocking of local capillary due to long period of local compression.
关键词: 烧伤 湿润 青霉素 治疗压疮 long period -
中药离子导入加骨刺贴治疗骨质增生症100例
BACKGROUND:Hyperosteogeny is often caused when walking or standing for a long period of time and certain postures must be kept.Traction or avulsion of muscles, hemorrhage and granulation of hematoma led to formation of spurs or lip liked hyperosteogeny.
关键词: 中药离子导入 骨刺贴 治疗 骨质增生症 long period -
一氧化碳中毒迟发脑病的高压氧治疗
INTRODUCTION Encephalopathy tarda of CO intoxication is the result of incomplete therapy or in- timely treatment of acut intermedium or severe CO intoxication leading to a series of nerve system injury.Due to long period of course,serious condition and unlcrear mechanism,therapy is difficult and poor effect.
关键词: 一氧化碳中毒迟发脑病 高压氧治疗 long period -
婴儿肝炎综合征与巨细胞病毒感染
本文对182例婴儿肝炎综合征患儿进行巨细胞病毒(CMV)检查,结果病毒分离及/或血清学阳性共92例,阳性率为50.55%.实验证明GMV在肝炎综合征的各种病原中占首位.除尿标本以外,少数患儿可从唾液及母乳中分离出来.反复检查证明有长期间歇排毒现象.本文从胆道闭锁婴儿的肝活组织及尸检肝组织中分离到CMV,从病毒学证明胆道闭锁的炎症学说,说明CMV.肝炎可能发展为胆道闭锁.从一例胆总管囊肿患儿的肝活组织亦分离到CNIV,说明CMV肝炎与胆总管囊肿亦有密切关系.
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精氨酸甲基转移酶在癌症发病机制中的作用
Tumor development of human takes multiple steps over a long period of time.The multiple steps with DNA mutations on genes is important for maintaining genome stability.Cell cycle and differentiation and epigenetic changes give rise to funor stem cells,which produce the mass of heterogeneous tumor cells.The cancer stem cell theory indicates that cancer cells are heterogeneous with a hierarchal structure,and only the cancer stem cells have the ability of self-renewal and to initiate tumorigenesis in a series of transplantation in xenograft models[1].
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先天性胆总管囊肿切除短段空肠代胆道手术——临床和实验研究
囊肿切除胆肠Roux-γ吻合术为治疗先天性胆总管囊肿通用的手术.但该手术存在三个问题:①全囊切除损伤面广、出血多、污染面大;②Roux-γ防返流空肠袢较长,本身迂益,易致胆汁淤滞及梗阻,增加感染及结石形成的机会;③胆汁引流至空肠改变了十二指肠正常生理环境.为此,我们进行了改进:①将囊肿之游离部分全层切除,配合小部分后壁内层切除,缩小了剥离面;②在肝总管和十二指肠之间,间置一短段空肠代胆道,使胆汁直接引流至十二指肠;③加用矩形瓣防止返流(1).称之为"囊肿切除短段空肠代胆道"手术.
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AIM:To observe the antineoplastic effect of Naja Naja atra venom (NNAV) on S180 bearing mice and to study the possible antineoplastic mechanism. METHODS:We observed the effect of NNAV on tumor weight、plasma nitric oxide content、plasma endothelin content and spleen index in S180 bearing mice with different concentration and different period by means of injecting into abdomen. RESULTS:Treatment with NNAV solution of different concentration could markedly inhibit S180 growth (especially in the low concentration group and by long period) and rate of inhibiting ranged from 21 63% to 49.25%; the plasma nitric oxide content, the plasma endothelin content and NO/ET ratio in tumor bearing mice were obviously higher than those of the normal control group, while after treatment with NNAV solution, the plasma nitric oxide level, the plasma endothelin level and NO/ET ratio could be reduced markedly, and it was noticed that NO/ET ratio in the group with highest inhibiting rate was most close to that of the normal control group. The spleen index was obviously increased after treatment with NNAV solution.CONCLUSION:The antineoplastic effect of NNAV on S180 bearing mice is best in long period by means of injecting into abdomen with low concentration. The mechanism of the antineoplastic effect of NNAV may be related to lowering the plasma nitric oxide and endothelin level, regulating the NO/ET ratio and enhancing the immune response.
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长期吸毒者多发性器官损害的临床分析
我们在临床工作中曾救治过许多因长期吸毒后出现复杂临床症状及多器官损害的病人.就其产生的原理不甚明了.为此查阅了大量相关资料,对该类病人病情的发生发展及相关症状产生的原因进行归类,并加以分析.报告如下.
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From Biology to Targeted Cancer Treatment and Prevention
Cancer is a complex disease involving accumulation of multiple molecular abnormalities during a long period of time. Because the differences in tim-ing and types of abnormalities, together with differences in inherited genetic background of individuals, patients with even same type cancer may experi-ence dramatically different clinical presentations and outcomes.