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从循证医学展望中医药临床研究与实践
循证医学(Evidence-based Medicine,EBM)是以证据为基础的医学.它强调从系统研究中获取证据,并重视临床实践中个人经验与系统研究中所获得的科学证据相结合,是临床流行病学和现代信息学与临床医学结合的典范,在国际临床医学领域正日益受到重视和普遍运用.循证医学在我国方兴未艾,借鉴循证医学模式开展中医药临床研究与实践,对提高中医药临床科研水平、解决中医临床的重大诊疗问题、推动中医药现代化进程使其走向世界具有重要意义.本文试从循证医学角度探讨中医药临床研究与实践的现状和发展趋势.
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细胞信号转导与抗肿瘤中药开发(下)
2 证的研究证的研究主要集中在脾虚证方面,重点在蛋白酪氨酸激酶、PKC系统、cAMP-PK系统和与免疫相关性的研究,其中cAMP-PK系统研究较多,但多集中于探讨cAMP、cGMP的含量及其比值.细胞内cAMP与cGMP是一对颉颃因子,曾被比作传统中医理论的"阴""阳".cAMP表达增高抑制肿瘤生长,而cGMP表达增强将使细胞处于分裂状态.
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活血通腑逐水治疗急性出血性脑卒中91例观察
急性脑出血是临床常见的重危病症,为现今死亡率高的三大疾病之一.国内外资料显示,其发病有明显增加趋势.相对于脑梗塞而言,针对脑出血的有效治疗较少.我们以活血破瘀、通腑逐水中药治疗急性脑出血,取得了较满意的疗效,报道如下.
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We studied Chinese and Uighur medicines and create an automated computer diagnostics system according to principals of Uighur medicine for evaluation of bronchial asthma patient′s state .498 patients with bronchial asthma were enrolled the automated computer diagnostic program .304 patients were evalu‐ated in the process of drug and non‐drug treatment .Savda asthma type of Uighur medicine do not corre‐sponds with any of the defined clinico‐pathogenetic variants of the disease .Thus ,prevailing of atopic bron‐chial asthma with probability of 0 .7 is defined with Savda categories with such as ‘Lungs energy deficien‐cy’ ,‘Spleen energy deficiency’ and ‘Kidneys Yin deficiency’ (P <0 .01) variants in Chinese Medicine . The combination of infectious‐dependent variant of bronchial asthma Abnormal Savda syndrome with atopy with a probability of 0 .8 is accompanied by the categories of ‘Hot and Full’ asthma with such variants as‘Lungs energy deficiency’ ‘Spleen energy deficiency’ ,‘Kidneys Yin deficiency’ (P < 0 .01) .Patients with an easier case of Abnormal Savda syndrome bronchial asthma in 71% of cases have prevailing diagnos‐tic categories of ‘External ,Full and Cold’ asthma .Patients with a harder case of Abnormal Savda in 74%of cases belongs to the categories of ‘Internal ,Empty and Hot’ asthma .So ,hormone dependency of the disease in 69% of cases is accompanied by the ‘Kidneys Yin deficiency’ variant and ,if there is an aspirin component in the pathogenesis of mixed asthma ,in 83% of cases ‘Kidneys Yin deficiency’ and ‘Kidneys Yang deficiency’ variants are defined .
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Chinese and Uighur medicine diagnostic criteria of the evaluation of the Modern drug treatment side-effects in bronchial asthma patients