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Background Hyperhomocysteinemia (prevalent in rural northern China)is an emerging risk factor for arterial endothelial dysfunction in CAD, which can be improved with folic acid supplementation. Such homocysteine-lowerying dosage of folio acid ( < 1 mg/d ) can reduce restenosis after PTCA, but not the cardiovascular events.Folic acid has additional vascular protection in antixidation, NO synthase protection, angiogenesis-promotion and cytokines reduction.
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Angiogenin is associated with the pathogenesis of diabetic peripheral neuropathy. Here, we se-quenced the coding region of the angiogenin gene in genomic DNA from 207 patients with type 2 diabetes mel itus (129 diabetic peripheral neuropathy patients and 78 diabetic non-neuropathy pa-tients) and 268 healthy controls. Al subjects were from the Han population of northern China. No mutations were found. We then compared the genotype and allele frequencies of the angiogenin synonymous single nucleotide polymorphism rs11701 between the diabetic peripheral neuropathy patients and controls, and between the diabetic neuropathy and non-neuropathy patients, using a case-control design. We detected no statistical y significant genetic associations. Angiogenin may not be associated with genetic susceptibility to diabetic peripheral neuropathy in the Han population of northern China.
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饮食健康教育在北方糖尿病病人社区护理中的应用
糖尿病是一种慢性、全身性、代谢性疾病,是由于相对或绝对胰岛素分泌不足所引起的糖、蛋白质、脂肪代谢紊乱.临床表现为多饮、多尿、消瘦和乏力等症状,严重者可出现心、脑、肾、视网膜等一系列并发症.所以,对健康人群的饮食指导及病人饮食护理的健康教育尤为重要.现将糖尿病饮食健康教育在北方社区糖尿病病人护理中的应用介绍如下.
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第十一届华北地区肾脏病研讨会暨北京2008年肾脏病学年会会议、河北省肾脏病学分会第四届第三次学术会议纪要
2008年6月19日至21日在河北省石家庄市举办了第十一届华北地区(北京、天津、河北、山西、内蒙古)肾脏病研讨会暨北京2008年肾脏病学年会、河北省肾脏病学分会第四届第三次学术会议.华北地区肾内科医师、内科医师、儿科医师及一些社区医生400余人参加了本次会议.