Objective: To observe the clinical effect of guava leaf (GL) in treating infantile rotaviral enteritis.Methods: Sixty-two patients of rotaviral enteritis were randomly divided into the treated group treated with GL and the control group treated with Gegen Qinlian Decoction. The time for ceasing diarrhea, content of Na+ in blood, content of Na+ and glucose in stool, and the rate of negative conversion of human rotavirus antigen (HRVA) were observed.Results: The 3-day recovery rate in the treated group (87.1%) was significantly higher than that in the control group (58.1%, P<0.05). The time of ceasing diarrhea in the treated group (25.1±9.5 hrs) was significantly shorter than that in the control group (38.7±15.2 hrs, P<0.01). Moreover, content of Na+ and glucose in stool were reduced obviously in the treated group but not in the control group; and negative conversion rate of HRVA in the former group also got better than that in the latter group (87.1% vs 58.1%, P<0.05). Consequently, the effect of GL was superior to that of the control significantly.Conclusion: GL has good curative effect on infantile rotaviral enteritis.

Objective:To find out the effective treatment for infantile autumn diarrhea(IAD).Methods:Retention enema with Qilian Liquid(QLL) was applied to 106 patients of IAD with positive antigen of rotavirus in stool,and the result in the treated group was compared with that in the control group(82 patients) in aspects of clinical effect, negative conversion rate of rotavirus in stool and change of serum immunoglobulin. Animal experimental study was also conducted.Results:The disappearance time of principal symptoms, negative conversion rate of rotavirus in stool and serum levels of IgA and IgG in the treated group were significantly better than those in the control group (P<0.01, P< 0.05). Experimental study showed that QLL not only has the anti-viral effects to stop diarrhea, but also has effects in enhancing immune function and protecting intestinal mucous membrane. Conclusion:Retention enema with QLL is an effective therapy for the treatment of IAD.

腹腔镜治疗>5 cm胃GIST是否安全可行：前瞻性队列研究结果

目的：由于担心术中肿瘤破裂，腹腔镜手术治疗>5 cm胃GIST仍存争议。方法：为探讨腹腔镜手术切除>5 cm胃GIST的可行性及安全性，我们于2011年3月至2015年3月入组一前瞻性研究队列。研究主要终点为术中肿瘤破裂发生率；次要终点包括：中转开腹率、手术时间、手术出血量、恢复流食及固体食物时间、术后住院时间及随访期间肿瘤复发率。结果：共有22例患者进入研究队列，平均肿瘤直径(7.04±1.53)cm，范围：(5.2~10.8cm)，无术中肿瘤破裂。平均手术时间(88.1±31.9)min，估计手术出血量(37.1±18.7)mL，无需输血病例。恢复流食及固体食物时间分别为(1.1±0.6)d及(2.5±0.9)d。平均术后住院时间为(5.4±5.8)d。平均随访时间为(18.9±10.2)月，范围：(2~47月)，随访期内无复发病例。结论：腹腔镜手术切除>5 cm胃GIST安全、可行。