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北京市儿童与肠道病毒71型感染有关的手足口病伴中枢神经系统症状一例
ASE REPORTA 9-year-and-8-month-old girl experienced intermittent headache of 2 d, fever of 1 d and convulsion of 2 h and was sent to the emergency room (ER). Two days before admission, the girl presented with intermittent headache of obscure cause, which had no fixed site and was tolerable, accompanied by dizziness; she had no change in vision, nor vertigo, nausea, vomiting, cough, nasal discharge or otalgia. One day before hospitalization, the girl became feverish, with the highest body temperature of 38. 8℃ while she had convulsions two hours before the visit to the ER, presenting with binocular gazing, trismus, loss of consciousness, initially noncyanotic face, unaccompanied by extremities rigidity or clonus. Her convulsion could not be controlled after intramuscular injection of 6 mg valium at the local clinic and was transferred to a neighboring secondary hospital 20 min later, where she began to develop extremities clonus, irregular respiration and cyanosis.
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裸花紫珠叶抑菌性物质的ASE联合牛津杯和微孔刃天青法筛选
目的 筛选6种不同极性溶剂提取物对6种常见菌抑菌性好的溶剂和菌株.方法 利用快速提取仪(ASE)和6种不同极性溶剂对裸花紫珠叶进行提取,对6种常见菌进行定性的牛津杯法抑菌实验;对大肠杆菌和枯草芽孢杆菌两种菌进行定量的微孔板刃天青法筛选实验,测定5种提取液对大肠杆菌和枯草芽孢杆菌作用测得的(低抑菌浓度)MIC值.结果 除了水提药液,其他5种对不同的菌有不同的抑菌圈,但乙醇和正丁醇段对大肠杆菌和枯草芽孢杆菌都有较好的抑菌圈;在相同作用条件下,相比其他3种提取药液,乙醇和正丁醇有较低的的抑菌浓度,分别为0.022g· m1-1和0.033g·ml-,但正丁醇比乙醇有较高的抑菌性和毒性.结论 终可筛选乙醇作为裸花紫珠叶的提取剂,且可以得出提取液药液对大肠杆菌和枯草芽孢杆菌有较好的抑菌性.
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ASE-GPC/GC/MS方法检验血中20种常见毒物
目的 建立血样中20种常见毒物的ASE-GPC/GC/MS检验方法.方法 血样采用快速溶剂萃取,GPC/GC/MS检验.结果 20种常见毒物平均回收率为85.3% ~99.1%,检出限为0.02μg/mL~0.03μg/mL.结论 该方法可满足实际检案的需求.