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1例使用热水袋导致芬太尼透皮贴中毒病人的抢救
1 病例介绍病人,女,46岁,发现肝癌6个月,近日食欲差,体重明显下降,肝区疼痛,疼痛不能忍受,睡眠受到干扰,夜间间断入睡,睡眠质量差,疼痛强度按数字分级法为中度,入院后第1天遵医嘱予以芬太尼透皮贴(多瑞吉每贴含芬太尼4.2 mg)贴于腹部,入院后第2天晚间病人突然出现意识模糊、四肢湿冷、呼吸浅慢、瞳孔缩小呈针尖样.
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多瑞吉治疗癌性疼痛65例疗效分析
Objective To evaluate the effect and toxicological reactions of Duoruifen in the management of cancer Pain. Method Transfer Fentanyl with trade name Duoruifen was applied to control chronically moderate to severe cancer pain in 65 cases. Change of drug was conducted once 72 hours, for 30~ 120 days. Observation indexes included pain intensity, relief rate, life satisfaction, quality of life, etc..Result Relief for moderate and severe cancer pain was 88.63% and 80.95% ,respectively.Alteration intercourse for 21.54% patients was reduced,and satisfaction was 93.84% . Quality of life was markedly improved. Incidence of constipation, vomiting, dizziness and nausea was 13.84% ,10.76% ,7.69% and 7.69% respectively.Conclusion Duoruifen is capable of effectively controlling cancer pain with good acceptability, adverse effect patients willing to accept it.