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第47课评价心脏同步化治疗疗效的现有标准一致性不足
Predicting whether a patient will benefit, or "respond," to cardiac resynchronization therapy (CRT) has been the focus of more than 500 publications during the last 5 years; however, the definition of response to CRT varies widely between studies, and numerous criteria to define a positive response1 to CRT exist in the literature."Echocardiographic" response is typically assessed by quantifying the change in left ventricular ejection fraction (LVEF) or left ventricular end-systolic volume (LVESV) 3 to 6 months after CRT implantation."Clinical" response is assessed with the increase in the distance walked in 6 minutes or improvement in New York Heart Association(NYHA) functional class 3 to 6 months after CRT implantation.Some studies have defined response to CRT as a combination of several clinical measures or as a combination of both clinical and echocardiographic measures.