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EBV编码miRNA与淋巴瘤发病机制的相关研究新进展
After infecting cells,EBV-encode microRNA (miRNA),a short,non-coding RNA,negatively regulates gene expression through attenuating target mRNA translation and stability.It is now apparent that many viral miRNAs may contribute to immortalization and immune evasion by targeting viral and cellular factors involved in host cell proliferation,apoptosis and immune responses.This article sums up the known target genes of EBV-encoded miRNAs and their functions,as well as their potential clinical value.
关键词： EBV编码microRNA 淋巴瘤 发病机制
