AIM To evaluate the pharmacological effect of phosphorus-32 glass microspheres (32p-GMS) injected intothe implanted human liver cancer cell mass in nude mice.METHODS Fifty-two Balb/c tumor loaded nude mice were allocated into treatment group (n =38) andcontrol group (n = 14), in the former group different doses of 32p-GMS were injected into the tumor mass,while in the latter group 31 P-GMS or no treatment were given instead of 32 P-GMS. After dynamicallyobserving the growth of tumor for d 3 - d 28, the experimental animals were killed in batches, the tumor andits nearby tissues were examined by light and electronic microscopy.RESULTS In comparing with the control group, the treatment group showed the tumor inhibiting rates of59.7% -93.6% (Variance analysis of the mean weight of different doses and control group after square rootcorrection, F= 579.62, P<0.01). As the tumor mass attained the absorbed dose of 7320Gy, the tumor cellswere completely destroyed and at this maximal dose in one case, the epithelial tissue neighboring to this massshowed the signs of metaplasia. When the absorbed doses ranged from 1830Gy to 3660Gy, most of the tumorcells showed the evidences of injury or necrosis, and some well differentiated tumor cells appeared. As theabsorbed dose being 366Gy or less, some tumor cells remained in active proliferative stage with a lot offibroblasts and lymphocytes presented in the neighboring interstitial tissues.CONCLUSION When the experimental model of implanted human liver cancer cells received 32p-GMS of1830Gy-3660Gy, it produces excellent anticancer action without any injury to the normal neighboringtissues and the prominent anticancer effect is found within d 3 after intratumor injection.

CT增强扫描在鉴别Castleman病病理类型中价值的研究

目的 探讨CT增强扫描在鉴别透明血管型和浆细胞型Castleman病中的价值.方法 回顾性分析14例经病理证实CD的CT平扫及增强病例资料,测量增强扫描各期CT值并作统计学分析.结果 11例为透明血管型,3例为浆细胞型,均为弥漫型(共6个病灶).11例透明血管型患者平均年龄为(35.92 ±15.58)岁,浆细胞型为(52.67 ±8.96)岁,统计学差异有意义(P＜0.05);透明血管型CT平扫、CT动脉期、CT静脉期,CT动脉-平扫、CT静脉-动脉的平均CT值分别为(42.30±4.37) HU、(126.01±26.20) HU、(106.65±18.54) HU、(86.05±24.63) HU、(-20.71±26.07) HU;浆细胞型CT平扫、CT动脉期、CT静脉期,CT动脉-平扫、CT静脉-动脉的平均值分别为(50.77±14.55) HU、(98.09±10.62) HU、(88.08±13.73) HU、(47.14±9.96)HU、(-9.61 ±4.80)HU;两种病理类型中CT动脉期、CT静脉期、CT动脉-平扫差异有统计学意义(P＜0.05、P＜0.05,P＜O.05),CT平扫和CT静脉-动脉差异无统计学意义(P ＞0.05,P＞0.05).结论 年龄、CT动脉期、CT静脉期、CT动脉-平扫在鉴别透明血管型和浆细胞型CD具有重要意义.

Quadricuspid pulmonic valve (QPV) is almost always a benign anomaly and is therefore usually discovered incidentally on radiographic studies or post-mortem at autopsy. Because of its rarity, the true extent of the physiology of QPV is not fully understood, and the few reported cases of it may underestimate its physiological consequences. In this case, we report on a young active-duty solider who presented for a well check-up and was discovered on imaging to have a QPV. We also review the most recent literature and provide recommendations regarding the most effective diagnostic modalities.