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曲美他嗪对陈旧性心肌梗死康复期运动耐量的影响
Objective To investigate the effect of trimetazidine(TMZ) on exercise capacity of the patients with old myocardial infarction during recovery period. Method 28 patients were administered hitrales, blockers and antipemic agents. 30 patients were administered TMZ 20 mg tid. After 12 weeks ,we compared nitrite expenditures, time to onset of angina after exercise, the time to 1 mm ST segment depression after exercise and rate pressure product. Result Nitrite expenditures per week were significantly reduced than before treatment and comprehensive group(P< 0.001). The rate pressure product of TMZ didn't change significantly(P >0.05). Conclusion TMZ may increase exercise capacity of patients with old myocardial infarction.
