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Journal of neurointerventional surgery 串联闭塞血管内治疗中急性血栓形成和双层颈动脉支架闭塞。

影响因子：8.572 DOI：10.1136/neurintsurg-2019-015032

作者： Pfaff JAR,Maurer C,Broussalis E,Janssen H,Blanc R,Dargazanli C,Costalat V,Piotin M,Runck F,Berlis A,Killer-Oberpfalzer M,Hensler JT,Bendszus M,Wodarg F,Möhlenbruch MA 发表时间：2020-07-10 14:30:39

from：《Journal of NeuroInterventional Surgery》

keywords： Pfaff JARMaurer CBroussalis EJanssen HBlanc RDargazanli CCostalat VPiotin MRunck FBerlis AKiller-Oberpfalzer MHensler JTBendszus MWodarg FMöhlenbruch MA

关键词：支架中风血栓切除术

Abstract

PURPOSE:To evaluate the occurrence and risk factors of acute in-stent thrombosis or stent occlusion in patients with tandem occlusions receiving intracranial mechanical thrombectomy and emergent extracranial internal carotid artery stenting with a dual layer carotid stent. METHODS:Multicenter retrospective data collection and analysis of stroke databases of seven comprehensive stroke centers from three European countries. RESULTS:Overall, 160 patients (mean (SD) age 66 (12) years; 104 men (65%); median (IQR) baseline NIHSS 14 (9-18); IV lysis, n=97 (60.6%)) were treated for a cervical carotid artery occlusion or stenosis using a CASPER stent (MicroVention), and received mechanical thrombectomy for an intracranial occlusion between April 2014 and November 2018. During the procedure or within 72 hours, formation of thrombus and complete occlusion of the CASPER stent was observed in 33/160 (20.8%) and in 12/160 patients (7.5%), respectively. In 25/33 (75.8%) and in 9/12 patients (75%), respectively, this occurred during the procedure. No statistically significant difference was observed between patients with and without thrombus formation with regard to pre-existing long term medication with anticoagulants or intraprocedural administration of heparin, acetylsalicylic acid (ASA), or heparin and ASA. Favorable early neurological outcome was similar in patients with (n=15; 45.5%) and without (n=63; 49.6%) thrombus formation at the CASPER stent. CONCLUSION:Acute thrombosis or occlusion of CASPER stents in thrombectomy patients receiving emergent extracranial internal carotid artery stenting for tandem occlusions were observed more often during the procedure than within 72 hours of follow-up, were less frequent then previously reported, and showed no impact on early neurological outcome.

摘要

用途: 评估双支架置入颅内机械取栓和颅外颈内动脉支架置入术串联闭塞患者急性支架内血栓形成或支架闭塞的发生情况及危险因素。方法: 欧洲 3 个国家 7 个综合性卒中中心卒中数据库的多中心回顾性数据收集和分析。结果: 总体上，160 例患者 (平均 (SD) 年龄 66 (12) 岁; 104 例男性 (65%); 中位 (IQR) 基线NIHSS 14 (9-18); IV松解，n = 97 (60.6%) 使用CASPER支架 (MicroVention) 治疗颈部颈动脉闭塞或狭窄，并在 2014 年 4 月至 2018 年 11 月期间接受了颅内闭塞的机械性血栓切除术。在手术过程中或 72 小时内，分别有 33/160 例 (20.8%) 和 12/160 例 (7.5%) 患者观察到血栓形成和CASPER支架完全闭塞。分别有 25/33 例 (75.8%) 和 9/12 例 (75%) 患者发生这种情况。在预先存在的长期抗凝药物治疗或术中给予肝素、乙酰水杨酸 (ASA) 方面，有和没有血栓形成的患者之间未观察到统计学显著差异。或者肝素和ASA。良好的早期神经功能预后在CASPER支架有 (n = 15; 45.5%) 和无 (n = 63; 49.6%) 血栓形成的患者中相似。结论: 在接受急诊颅外颈内动脉支架置入术治疗串联闭塞的血栓切除术患者中，CASPER支架急性血栓形成或闭塞的发生率高于随访 72 小时内。比以前报道的频率低，对早期神经系统预后无影响。

期刊介绍

《Journal of NeuroInterventional Surgery》 (点击进入期刊详情)

英文简介 : The Journal of NeuroInterventional Surgery (JNIS) is a leading peer review journal for scientific research and literature pertaining to the field of neurointerventional surgery. The journal was launched in 2009 following growing professional interest in neurointerventional techniques for the treatment of a range of neurological and vascular problems including stroke, aneurysms, brain tumors, and spinal disorders. JNIS is published by BMJ on behalf of SNIS, it is also the official journal of ESMINT, the Interventional Chapter of ANZSNR, CING, HKSITN and the INR Chapter of NRST. JNIS publishes regular podcasts of interviews with the authors of highlighted papers. Discover them here.

中文简介 : （来自Google、百度翻译）《神经介入外科杂志》（JNIS）是一个领先的同行评审期刊，用于科学研究和有关神经介入外科领域的文献。2009年，随着对神经介入技术越来越感兴趣，该杂志开始发行，用于治疗一系列神经和血管问题，包括中风、动脉瘤、脑肿瘤和脊柱疾病。JNIS由BMJ代表SNIS出版，同时也是ESMINT的官方刊物、ANZSNR的介入章节、ICE、HKSITN和NRST的INR章节。 JNIS在这里定期发布与重点论文作者的访谈播客。

CIRCULATION RESEARCH 期刊中科院评价数据

新中科院分区

大类(学科)	小类(学科)	学科排名
医学	NEUROIMAGING (神经成像) SURGERY (外科)	6/14 29/200

大类(学科)

小类(学科)

学科排名

医学

NEUROIMAGING (神经成像)

SURGERY (外科)

6/14
29/200

新发布的期刊年发文量

年度总发文量	年度论文发表量	年度综述发表量
264	241	23

总被引频次 :4407

特征因子 : 0.011860

影响因子趋势图

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