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Heart, lung & circulation 霉菌性冠状动脉瘤。
影响因子:2.838 DOI:10.1016/j.hlc.2018.12.004
作者: Baker DW,Whitehead NJ,Barlow M 发表时间:2020-07-09 12:20:34
keywords: Baker DWWhitehead NJBarlow M
关键词: 冠状动脉瘤 霉菌性冠状动脉瘤
Abstract
BACKGROUND:Mycotic coronary aneurysms (MCA) are rare but often lead to significant morbidity and mortality. Evidence on the topic is limited to case reports and small case series. A systematic review was performed to improve understanding of this challenging diagnosis. A case report prompting this review is also included. METHODS:Relevant articles were identified by searching databases Medline and Google Scholar for terms 'mycotic coronary aneurysm'. Manual searching from article references identified further case reports. RESULTS:Ninety-seven (97) published cases of MCA were identified between 1812 and 2017; 80 cases since the introduction of percutaneous coronary intervention (PCI) with stents in 1986. The most common associations were PCI (40.0%) and infective endocarditis (IE) (40.0%). Complications including aneurysm rupture (28.9%), pericardial effusion (37.3%) and myocardial infarction (39.8%) were frequent. Short-term mortality was high at 42.6%. The most common treatment was surgical resection of the aneurysm with bypass grafting. CONCLUSIONS:We present a case and the largest systematic review to date of this rare diagnosis, identifying 97 published case reports. Clinical scenarios in which to consider MCA include febrile illness after recent PCI, febrile illness (particularly infective endocarditis) with evidence of coronary ischaemia, and purulent pericarditis. Given the high rate of complications and mortality, immediate surgical referral is recommended.
摘 要
背景: 霉菌性冠状动脉瘤 (MCA) 罕见,但常导致显著的发病率和死亡率。关于该主题的证据仅限于病例报告和小病例系列。进行了系统回顾,以提高对这一具有挑战性的诊断的理解。还包括提示本次审查的病例报告。 方法: 通过检索数据库Medline和Google Scholar中的 '霉菌性冠状动脉瘤' 确定相关文章。从文章参考文献中手动搜索确定了进一步的病例报告。 结果: 在 1812-2017 之间确定了 97 例 (97 例) 已发表的MCA病例; 自 1986 年采用支架经皮冠状动脉介入治疗 (PCI) 以来,确定了 80 例。最常见的关联是PCI (40.0%) 和感染性心内膜炎 (IE) (40.0%)。并发症包括动脉瘤破裂 (28.9%) 、心包积液 (37.3%) 和心肌梗死 (39.8%)。短期死亡率高达 42.6%。最常见的治疗方法是手术切除动脉瘤并旁路移植术。 结论: 我们介绍了迄今为止关于这一罕见诊断的病例和最大的系统综述,确定了 97 份已发表的病例报告。考虑MCA的临床情况包括近期PCI后的发热性疾病、有冠状动脉缺血证据的发热性疾病 (特别是感染性心内膜炎) 和化脓性心包炎。鉴于并发症和死亡率高,建议立即手术转诊。
期刊介绍
《Heart Lung and Circulation》 (点击进入期刊详情)
英文简介 : Published by Elsevier Science. ISSN (printed): 1443-9506. ISSN (electronic): 1444-2892. Heart Lung & Circulation formerly known as The Asia Pacific Heart Journal is a peer-r
中文简介 : (来自Google、百度翻译) 由爱思唯尔科学出版。ISSN(印刷):1443 - 9506。ISSN(电子):1444 - 2892。 《心肺循环》以前被称为《亚太心脏杂志》,是一本同行杂志
CIRCULATION RESEARCH 期刊中科院评价数据
新中科院分区
大类(学科) 小类(学科) 学科排名
医学

CARDIAC & CARDIOVASCULAR SYSTEMS (心脏和心血管系统)

76/128
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年度总发文量 年度论文发表量 年度综述发表量
182 142 40

总被引频次 :2503

特征因子 : 0.006030

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