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重型精神病性抑郁症文献资料
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糖皮质激素受体与重型精神病性抑郁症的治疗
1 IntroductionPsychotic major depression (PMD),which responds poorly to tricyclic anti-depressants, is a distinct syndrome of depression. hy percortisolemia (cortisone hypersecretion), a biological abnormality existing in many patients with PMD, has led to various theoretical and empirical rationales for the potential therapeutic use of anti-glucocorticoid agents in the treatment of depression.