ECAPs are the summary of multiple neurons’ spikes which could be recorded by a bidirectional stimulation-recording system via the cochlear implant, with the artifact elimination paradigms of forward-masking subtraction paradigm or alternating polarity paradigm. Three kinds of FDA approved cochlear implants support ECAP testing. This article is to summarize the clinical application of ECAP test. ECAP test after insertion of electrode during implant operation has been widely used during cochlear implant surgery. In recent years, ECAP thresholds are also used to estimate the T levels and C levels helping programming. However, correlation between ECAP thresholds and psychophysical thresholds is affected by many factors. So far, ECAPs cannot yet be a good indicator of post-operative hearing and speech performance.

The study reports a case of a 5-year-old Chinese girl diagnosed with Kabuki make-up Syndrome (KMS). The patient showed classic KMS appearance: widely separated eyes, ectropion of lateral one-third lower eyelids, flat nasal tip, and prominent ears. Auditory features in this individual included bilateral severe sensorineural hearing loss and lack of 40 Hz AERP responses identified at 1 year of age. The individual received cochlear implant (CI) in the left ear when 5 years old, and rehabilitation after CI treatment were 3 in speech intelligibility and 5 in auditory performance. Thus, our findings suggest that cochlear implant may be helpful to restore hearing for individuals with Kabuki syndrome. Copyright ? 2015, PLA General Hospital Department of Otolaryngology Head and Neck Surgery. Production and hosting by Elsevier (Singapore) Pte Ltd. All rights reserved.

Auditory Plasticity Induced by Cochlear Implants in Early Life

人工电子耳蜗植入是对重度或完全感音神经性聋患者建立听觉功能的有效装置.但是不同个体耳蜗植入后的效果,即言语识别能力之差别甚大.除了家庭、社会所能提供的术后服务与支持的差别以外,电子耳蜗移植的效果很大程度上决定于植入者中枢神经系统在电子耳蜗下发生可塑性改变的能力.另一方面电子耳蜗和其他电刺激装置的出现对听觉中枢可塑性改变和机制的研究提供了有力的工具.本文从电子耳蜗临床应用的角度出发,重点总结了近年来国外关于电子耳蜗或其他类似慢性电刺激装置植入后在先天性或语前聋个体听觉中枢通路产生的可塑性改变的研究进展,通过对已有资料的分析,探讨可塑性改变的特征、影响因素、可能机理以及对临床工作的意义.