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中国与加拿大合作开展健康与衰老研究的情况介绍
Improving health care in later life is crucial, especially under the impact of world population ageing. It provides challenges and opportunities for health and ageing research, and global co-operations and joint commitments among different countries are needed. Supported by the Canada-China Joint Health Research Initiative Program, the Canada China Study in Ageing and Longevity is the first research of the kind to compare the process of ageing and health changes between Canadian and Chinese. The collaboration sets up a data and knowledge sharing agreement between the participate partners. The initial proposal was for the " Quantification of health status changes in China and in Canada: an evaluation of a stochastic model of health transition". As the project evolves, however, the focus is expanding to develop a quantative method to assess frailty in elderly Chinese people, corresponding to information collected in Canada in Comprehensive Geriatric Assessments (CGAs). The Canadian team has established the Frailty Index and a stochastic ageing model, which despite mathematically simplicity, can capture characteristic health statue changes. The model will be applied to study Chinese datasets and parameters will be compared between different countries. In additional, a new version of the Frailty Index, based on a CGA (the FI-CGA) will be developed, tested and modeled. Through various research activities, the collaborative research will allow quantification not only of the impact of ageing, but also of the impact of a feasible intervention on improving public health in different social settings.
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衰弱与血管性痴呆
衰弱(Frailty)是与年龄相关的、涉及多个生理系统储备与功能下降引起的临床综合征[1].临床上有两个常用的衰弱定义.Rockwood等[2]提出衰弱定义(1994)的实质是一个累计负担指数,包括健康状况和缺陷(包含认知损害).Fried等[3](2001)提出衰弱应满足以下标准中的至少3条:握力下降;疲劳感;步行速度减慢;躯体活动降低;无预期的体质量减轻.
