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This clinical study was designed to determinate the value of colon microbiota microflora in colorectal cancer patients.We investigate pre-and post-operation stool samples in patients with different tumor localizations, trying to correlate those to postoperative complications.Our findings shows that if opportunistic pathogenic micro-flora levels are elevated before operations,it can lead to further microbiota disbalance in postoperative period,espe-cially in cases of antibacterial prophylaxis or treatment.Further,this changes increase a chance of receiving some complications after surgery.So,we suggest an analysis of stool microbiota in patients with colorectal cancer to be performed prior and after the operation.Furthermore,a perioperative decontamination therapy should be performed in cases of pathogenic microflora levels elevation.Still,monitoring a perioperative microbiota changes is not a routine in most recommendations and we assume that including this relatively unencumbered patient testing in pre-operative survey will help to reduce a number of postoperative complications.
