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This review describes disseminated intravascular coagulation(DIC) as a syndrome in which hemostatic factors are activated and products are generated. This syndrome ranges in severity from an obvious decompensated coagulopathy (overt-DIC) to the subclinical compensated activation of hemostatic factors(non-overt DIC). Ths first part of this review emphasizes two points: First, activation of the hemostatic system is controlled by a vast network of capillaries and venules through anticoagulant and antiinflammatory regulatory factors that operate from the endothelium( e. G. , protein C and thrombomodulin, tissue factor pathway inhibitor).
相关标签
- Drug targeting
- Antibody-mediated thrombolysis
- Catheter-directed administration
- Nanoparticletargeted fibrinolysis
- Vascular diseales
- Antithrombotic agents
- Trentment
- Hypercoagulable state
- Markers
- Hemostatic mechanism Molecular marker Platelet activation Endothelial damage Coagulation Anticoagulation Fibrinolysis