首页 > 文献资料
-
Objective:This study examined the prognosis of the “node-negative with eLNs≤15” designation and the additional value of incorporating it into the pN1 designation in the seventh edition N classification.Methods: From Jan 2000 to Sep 2010, a total of 1,258 gastric cancer patients undergoing radical gastric resection were enrolled. We incorporated node-negative patients with eLNs≤15 into pN1 and compared this designation with the 7th edition UICC N stage for 3.5- year overall survival by univariate and multivariate analysis. Homogeneity, discriminatory ability, and monotonicity of gradients in hypothetical N stage and UICC N stage were compared using linear trendχ2, likelihood ratioχ2 statistics, and Akaike information criterion (AIC) calculations.Results:Node-negative patients with eLNs≤15 had worse survival compared with those with eLNs >15. The hypothetical N stage had higher linear trend and likelihood ratioχ2 scores and smaller AIC values compared with those for the 7th edition N stage, which represented the optimum prognostic stratification.Conclusion:Node-negative patients with eLNs≤15 can be considered to be incorporated into the pN1 stage in the 7th edition of th e TNM classiifcation.
