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Abstract:
:The objective of our study is to estimate the radiation exposure to pediatric patients with sarcoma getting required (or highly recommended) ionizing radiation scans during initial chemotherapy and to determine how often distant progressive disease was discovered. Data from the last 25 years from the Children's Oncology Group open phase III protocols were reviewed for the most common pediatric sarcomas: osteosarcoma, Ewing's sarcoma, and rhabdomyosarcoma. The number of required/recommended ionizing radiation scans, including chest radiographs, chest computed tomography, positron emission tomography scans, and bone scans during induction, consolidation, and maintenance chemotherapy, were recorded and the total radiation dose per patient was calculated. In addition, the number of patients who were removed from protocol during chemotherapy because of new or distant progressive disease was documented. In our analysis of 5845 patients, the average pediatric patient with sarcoma on protocol was exposed to an ionizing radiation dose of 37.1 mGy, equivalent to the lifetime dose of nuclear power plant workers, whereas the progression of disease was detected at most in 5.4% of the patients. Our study is meant to inform pediatric oncologists more precisely of the actual risks and benefits of mandated surveillance scans during chemotherapy in patients with sarcoma.
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最新影响因子:1.17 | 期刊ISSN:1077-4114 | CiteScore: |
出版周期:Bimonthly | 是否OA:YES | 出版年份:1995 |
期刊官方网址:http://journals.lww.com/jpho-online/pages/default.aspx
自引率:5.00% | 研究方向:医学-小儿科 |
出版地区:UNITED STATES |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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Published by Lippincott Williams and Wilkins. ISSN: 1077-4114. The Journal of Pediatric Hematology / Oncology reports on major advances in the diagnosis and treatment of cancer and blood diseases in children. Each bimonthly issue presents informative case studies and original research articles from leading clinicians and investigators worldwide. Also featured are specially developed Continuing Seminars, which serve the continuing education needs of physicians by offering new insights into many areas of interest, as well as analyses of radiological problems in pediatric hematology / oncology and discussions of pertinent ethical and legal issues.
由Lippincott Williams和Wilkins出版。ISSN: 1077 - 4114。 《儿科血液学/肿瘤学杂志》报告了在儿童癌症和血液疾病的诊断和治疗方面的重大进展。每一期双月刊提供来自世界领先临床医生和研究人员的有价值的案例研究和原创研究文章。专题还包括专门开发的持续研讨会,通过对许多感兴趣的领域提供新的见解,分析儿科血液学/肿瘤学中的放射学问题,讨论相关的伦理和法律问题,从而满足医生的继续教育需求。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
HEMATOLOGY (血液学) 4区 ONCOLOGY (肿瘤学) 4区 PEDIATRICS (儿科) 4区 |
65/71 213/223 98/124 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
242 | 224 | 18 |
引文计数(2018)
文献(2015-2017)
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研究方向:儿童血液
审稿时间: 3个月内 接受率: 比较困难(25%命中)
影响因子:1
ISSN:1758-1559
研究方向:农林科学-奶制品与动物科学
影响因子:1.656
ISSN:0009-4293
研究方向:化学-化学综合
影响因子:0.638
ISSN:0235-7216
研究方向:化学-化学综合
影响因子:0.354
ISSN:0001-9704
研究方向:化学-化学综合
影响因子:1.145
ISSN:0100-4042
研究方向:化学-化学综合
影响因子:4.036
ISSN:2046-2069
研究方向:chemical sciences-
影响因子:3.21
ISSN:2192-6506
研究方向:CHEMISTRY, MULTIDISCIPLINARY-
影响因子:2.63
ISSN:2191-1363
研究方向:CHEMISTRY, MULTIDISCIPLINARY-
影响因子:0.356
ISSN:0009-2770
研究方向:化学-化学综合
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY 投稿经验
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