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Abstract:
PURPOSE:To evaluate the role of multimodal imaging in the diagnosis and monitoring of patients with osteogenesis imperfecta complicated with choroidal neovascularization. CASE REPORT:A 28-year-old man, diagnosed with osteogenesis imperfecta, was referred 2 months after the appearance of central scotoma and metamorphopsia in the right eye. The patient underwent a complete ophthalmological evaluation including visual acuity examination as well as ophthalmoscopy, spectral-domain optical coherence tomography, optical coherence tomography angiography, fundus autofluorescence imaging, fluorescein angiography and microperimetry. Complete examination revealed macular lacquer crack with subretinal haemorrhage. A further investigation with spectral-domain optical coherence tomography and fluorescein angiography revealed the presence of choroidal neovascularization without clear activity associated to the lacquer crack. After a 1-month follow-up, both visual acuity and retinal sensitivity improved spontaneously. CONCLUSION:Collagen deficiency of osteogenesis imperfecta leads to fragility of the Bruch's membrane; tension forces probably act at this level determining ruptures with bleeding and choroidal neovascularization formation. Multimodal imaging and functional evaluation are needed to assess retinal alterations in patients with osteogenesis imperfecta, whereas treatment of choroidal neovascularization should be reserved only for active lesion to prevent evolution and visual acuity decrement.
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最新影响因子:1.922 | 期刊ISSN:1120-6721 | CiteScore:1.27 |
出版周期:Bi-monthly | 是否OA:YES | 出版年份:1991 |
期刊官方网址:http://www.eur-j-ophthalmol.com/public/ejo/default.aspx
自引率:5.40% | 研究方向:医学-眼科学 |
出版地区:ITALY |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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A bi-monthly peer-reviewed original research journal reporting clinical observations and laboratory investigations with clinical relevance. Focuses on new diagnostic and surgical techniques, instrument and therapy updates, results of clinical trials and research findings.
两个月一次的同行评审的原始研究期刊,报告临床观察和具有临床相关性的实验室研究。重点介绍新的诊断和外科技术、仪器和治疗更新、临床试验结果和研究结果。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
OPHTHALMOLOGY (眼科学) 4区 |
31/59 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
147 | 143 | 4 |
引文计数(2018)
文献(2015-2017)
521次引用
411篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Medicine
小类(学科):Ophthalmology
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#49/108
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研究方向:医药科学 眼科学 视觉、视光学与近视、弱视及眼肌疾病
审稿时间: 2个月内
影响因子:1.992
ISSN:1976-1457
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影响因子:4.807
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影响因子:4.725
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研究方向:-
影响因子:5.551
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研究方向:医学-内分泌学与代谢
影响因子:0.704
ISSN:0985-0562
研究方向:医学-内分泌学与代谢
发表一篇学和医学成像类SCI论文
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