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Abstract:
INTRODUCTION:Multi-vessel coronary artery disease (MV-CAD) is common among patients with acute coronary syndrome (ACS) and is associated with worse outcomes. OBJECTIVES:To examine temporal trends of patients presenting with ACS and MV-CAD. METHODS:Time-dependent analysis of patients enrolled in the ACS Israeli Surveys (ACSIS) between 2004-2016 by 3 time periods: early (2004-2006; n = 2111), mid (2008-2010; n = 2049), and late (2013-2016; n = 2010). MV-CAD was defined as >50% stenosis in ≥2 separate coronary territories at the index coronary catheterization. Outcomes were 30-day MACE and 1-year all-cause mortality. RESULTS:Overall 6170/9321 patients (66%) had MV-CAD (age 64.5 ± 12.1, males 80%). Patients from later periods were older with a higher prevalence of cardiovascular risk-factors and comorbidity. Among patients with MV-CAD, STEMI decreased significantly (early-46% vs. late-37%, p < 0.001). The rates of PCI were similar, however rates of MV-PCI have increased (early-16.8% vs. late -37.1%, p < 0.001) while the rates of CABG decreased over-time (early-12.7% vs. late -9.2%, p < 0.001). Thirty-day outcomes improved significantly; MACE (early-18.2%, mid-12.6%, late-11.2%, p < 0.001), mortality (early-4.7%, mid-4.2%, late-3.1%, p = 0.03) and re-infarction (early = 3.0%, mid = 2.4% and late 1.1%, p < 0.001). No significant change in 1-year mortality was observed (early = 9.3%, mid = 7.8%, late = 7.7%, p = 0.13). A multivariate adjusted analysis demonstrated that the mid and late periods (vs. the early period) were associated with significantly reduced risk for 30-day MACE (OR = 0.65 [0.54-0.77] and 0.54 [0.45-0.65], respectively). CONCLUSIONS:During the last decade, the burden of cardiovascular risk factors among ACS patients with MV- CAD has increased, more invasive treatment was provided and a significant improvement in 30-day outcomes was observed.
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最新影响因子:4.039 | 期刊ISSN:0167-5273 | CiteScore:1.76 |
出版周期:Semimonthly | 是否OA:YES | 出版年份:1981 |
期刊官方网址:http://www.elsevier.com/wps/find/journaldescription.cws_home/506041/description#description
期刊投稿地址:http://ees.elsevier.com/ijc/
自引率:8.80% | 研究方向:医学-心血管系统 |
出版地区:IRELAND |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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The International Journal of Cardiology is devoted to cardiology in the broadest sense. Both basic research and clinical papers can be submitted. The journal serves the interest of both practicing clinicians and research workers.Editorials, Brief Reports and Review Articles covering recent developments are included. Controversial techniques, issues on health policy and social medicine are discussed and serve as useful tools for encouraging debate.International Journal of Cardiology has no page charges.A reduced personal subscription rate is available; please apply to the Publisher for more information.
《国际心脏病学杂志》在最广泛的意义上致力于心脏病学。基础研究和临床论文都可以提交。该杂志为临床医师和研究工作者提供了服务,包括社论、简要报告和评论文章。讨论有争议的技术、健康政策和社会医学问题,并作为鼓励辩论的有用工具。国际心脏病杂志不收取页面费用。可降低个人订阅率;请向出版商申请了解更多信息。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
CARDIAC & CARDIOVASCULAR SYSTEMS (心脏和心血管系统) 3区 |
41/128 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
1199 | 1085 | 114 |
引文计数(2018)
文献(2015-2017)
11795次引用
6683篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Medicine
小类(学科):Cardiology and Cardiovascular Medicine
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#113/327
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研究方向:医学 儿科
审稿时间: 6个月内
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研究方向:抗凝 抗栓 药物基因组学
审稿时间: 2个月内 接受率: 比较困难(25%命中)
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审稿时间: 2个月内 接受率: 比较困难(25%命中)
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审稿时间: 3个月内
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审稿时间: 2个月内 接受率: 比较困难(25%命中)
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审稿时间: 3个月内 接受率: 中等(50%命中)
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影响因子:13.029
ISSN:1522-8517
研究方向:医学-临床神经学
影响因子:4.506
ISSN:0167-594X
研究方向:医学-临床神经学
影响因子:7.723
ISSN:2162-402X
研究方向:ONCOLOGYIMMUNOLOGY-IMMUNOLOGY
影响因子:4.912
ISSN:1524-9557
研究方向:医学-免疫学
影响因子:12.02
ISSN:2326-6066
研究方向:ONCOLOGY-IMMUNOLOGY
影响因子:3.698
ISSN:1750-9378
研究方向:ONCOLOGY-IMMUNOLOGY
影响因子:6.63
ISSN:0340-7004
研究方向:医学-免疫学
影响因子:3.077
ISSN:1534-7354
研究方向:医学-全科医学与补充医学
影响因子:0
ISSN:1868-8497
研究方向:ONCOLOGY-ENDOCRINOLOGY & METABOLISM
INTERNATIONAL JOURNAL OF CARDIOLOGY 投稿经验
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