Maternal serum lipid in women with preeclampsia in Lagos: a case control study.

Abstract:
:Objective: This was to determine the serum lipid profile of preeclamptic women and their association with severity of preeclampsia.Methods: This was a case control study conducted at the Lagos University Teaching Hospital, Lagos, Nigeria. Blood samples for serum lipid estimation were collected after an overnight fast. The National Cholesterol Education Program - Adult Treatment Panel (ATP) III criteria were used to define dyslipidemia.Results: Two hundred forty women participated in the study. The mean total cholesterol of preeclamptic and normotensive women was 309.9 ± 10.4 mg/dl and 237 ± 6.8 mg/dl, respectively. Both groups of women had higher than normal mean levels of triglycerides (TG) (203.3 ± 11.0 mg/dl versus 157.5 ± 7.1 mg/dl); low-density lipoprotein (LDL)-c (156.5 ± 11.0 mg/dl versus 109.7 ± 6.9 mg/dl); high-density lipoprotein (HDL)-c (63.2 ± 2.5 mg/dl versus 55.4 ± 1.8 mg/dl) and very low-density lipoprotein (VLDL) (39.5 ± 2.0 mg/dl versus 31.5 ± 1.4 mg/dl). Fewer women with preeclampsia had isolated hypertriglyceridemia (95 versus 99%). Maternal serum total cholesterol (TC), TG, and LDL was significantly (p < .001) higher in severe, compared to mild preeclampsia. Pearson's correlation indicated that all lipids, including total cholesterol (r = 0.406) had positive correlation with preeclampsia.Conclusion: There is elevated serum lipid in pregnancy irrespective of preeclampsia developing. The positive correlation of maternal serum lipids to preeclampsia suggests a casual relationship.
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Journal of Maternal-Fetal & Neonatal Medicine
J MATERN-FETAL NEO M
最新影响因子:2.323 | 期刊ISSN:1476-7058 | CiteScore:N/A |
出版周期:Monthly | 是否OA:YES | 出版年份:2002 |
自引率:9.00% | 研究方向:医学-妇产科学 |
出版地区:ENGLAND |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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Journal of Maternal-Fetal & Neonatal Medicine 期刊简介
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欧洲围产期医学协会、亚洲和大洋洲围产期协会和国际围产期产科医生协会的官方期刊
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欧洲围产期医学协会、亚洲和大洋洲围产期协会和国际围产期产科医生协会的官方期刊
Journal of Maternal-Fetal & Neonatal Medicine 期刊中科院评价数据
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大类(学科) | 小类(学科) | 学科排名 |
医学 |
OBSTETRICS & GYNECOLOGY(产科医学和妇科医学) 4区 |
62/82 |
最新公布的期刊年发文量
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
539 | 498 | 41 |
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1 |
大类(学科):Medicine
小类(学科):Obstetrics and Gynecology
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#0/168
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