
发表一篇学和医学成像类SCI论文
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Abstract:
BACKGROUND:Stillbirth is a devastating adverse pregnancy outcome which may occur without any obvious reason, or may occur in the context of fetal growth restriction, preeclampsia or other obstetric complications. There is increasing evidence that women who experience stillbirths are at higher risk of long-term cardiovascular disease (CVD), but little is known about their risk of chronic kidney disease (CKD) and end-stage renal disease (ESRD). We conducted the largest study to date to investigate the subsequent risk of maternal CKD and ESRD following stillbirth. OBJECTIVE:To identify whether pregnancy complicated by stillbirth is associated with subsequent risk of maternal CKD and ESRD, independent of underlying medical or obstetric comorbidities. STUDY DESIGN/METHODS:We conducted a population-based cohort study using nationwide data from the Swedish Medical Birth Register, National Patient Register and Swedish Renal Register. We included all women who had live births and stillbirths from 1973 to 2012, with follow-up to 2013. Women with pre-existing renal disease were excluded. Cox proportional hazard regression models were used to estimate adjusted hazard ratios (aHR) and 95% confidence intervals (CI) for associations between stillbirth and maternal CKD and ESRD respectively. We controlled for maternal age, year of delivery, country of origin, parity, body mass index, smoking, gestational diabetes, preeclampsia, and small for gestational age (SGA) deliveries. Women who had a history of medical comorbidities, which may predispose to renal disease (pre-pregnancy CVD, hypertension, diabetes, lupus, systemic sclerosis, hemoglobinopathy, or coagulopathy), were excluded from the main analysis and examined separately. RESULTS:There were 1,941,057 unique women who had 3,755,444 singleton pregnancies, followed up over 42,313,758 person-years. The median follow-up time was 20.7 years (interquartile range 9.9-30.0 years). 13,032 women (0.7%) had at least one stillbirth. Women who had experienced at least one stillbirth had a higher risk of developing CKD (adjusted hazard ratio (aHR) 1.26, 95% CI 1.09-1.45) and ESRD (aHR 2.25, 95% CI 1.55-3.25) compared to women who only had live births. These associations persisted after removing all stillbirths which occurred in the context of preeclampsia, SGA or congenital malformations (for CKD, aHR 1.33, 95% CI 1.13-1.57; for ESRD, aHR 2.95, 95% CI 1.86-4.68). There was no significant association observed between stillbirth and either CKD or ESRD in women who had pre-existing medical comorbidities (CKD, aHR 1.13, 95% CI 0.73-1.75; ESRD, aHR 1.49, 95% CI 0.78-2.85). CONCLUSION:Women who have a history of stillbirth may be at increased risk of CKD and ESRD compared to women who have only had live births. This association persists independently of preeclampsia, SGA, maternal smoking, obesity, and medical comorbidities. Further research is required to determine whether affected women would benefit from closer surveillance and follow-up for future renal disease.
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最新影响因子:10.693 | 期刊ISSN:0002-9378 | CiteScore:3.5 |
出版周期:Monthly | 是否OA:YES | 出版年份:1920 |
期刊官方网址:http://www.ajog.org/
自引率:11.90% | 研究方向:医学-妇产科学 |
出版地区:UNITED STATES |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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The American Journal of Obstetrics and Gynecology, “The Gray Journal”, covers the full spectrum of Obstetrics and Gynecology. The aim of the Journal is to publish original research (clinical and translational), reviews, opinions, video clips, podcasts and interviews that will have an impact on the understanding of health and disease and that has the potential to change the practice of women's health care. An important focus is the diagnosis, treatment, prediction and prevention of obstetrical and gynecological disorders. The Journal also publishes work on the biology of reproduction, and content which provides insight into the physiology and mechanisms of obstetrical and gynecological diseases.
美国妇产科杂志,“灰色杂志”,涵盖了妇产科的所有领域。该杂志的目的是发表原创研究(临床和翻译)、评论、意见、视频剪辑、播客和访谈,这些将对健康和疾病的理解产生影响,并有可能改变妇女保健的做法。妇产科疾病的诊断、治疗、预测和预防是一个重要的研究重点。该杂志还出版了生殖生物学方面的著作,内容涉及妇产科疾病的生理学和机制。 好处的作者
大类(学科) | 小类(学科) | 学科排名 |
医学 |
OBSTETRICS & GYNECOLOGY (妇产科学) 1区 |
2/82 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
343 | 310 | 33 |
引文计数(2018)
文献(2015-2017)
6254次引用
1788篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Medicine
小类(学科):Obstetrics and Gynecology
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#5/168
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liting7111
研究方向:妇产科
liting7111
研究方向:妇产科
审稿时间: 2个月内
liting7111
研究方向:妇科肿瘤
审稿时间: 2个月内 接受率: 比较困难(25%命中)
liting7111
研究方向:临床 流行病学 妇科学
审稿时间: 2个月内 接受率: 比较困难(25%命中)
liting7111
liting7111
研究方向:妇产科
审稿时间: 2个月内 接受率: 比较困难(25%命中)
影响因子:1
ISSN:1758-1559
研究方向:农林科学-奶制品与动物科学
影响因子:1.656
ISSN:0009-4293
研究方向:化学-化学综合
影响因子:0.638
ISSN:0235-7216
研究方向:化学-化学综合
影响因子:0.354
ISSN:0001-9704
研究方向:化学-化学综合
影响因子:1.145
ISSN:0100-4042
研究方向:化学-化学综合
影响因子:4.036
ISSN:2046-2069
研究方向:chemical sciences-
影响因子:3.21
ISSN:2192-6506
研究方向:CHEMISTRY, MULTIDISCIPLINARY-
影响因子:2.63
ISSN:2191-1363
研究方向:CHEMISTRY, MULTIDISCIPLINARY-
影响因子:0.356
ISSN:0009-2770
研究方向:化学-化学综合
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY 投稿经验
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