AIM To investigate the effects of collagen solution on the prevention of acute gastric mucosal injury inrestricted rats inflicted by cooling in low temperature (4℃),METHODS Thirty healthy Wistar rats were randomly divided into normal (N, n = 10),injury (I, n = 10)and prevention (P, n = 10) groups. The rats were fasted for 48 h but free access to water without restrictionand cooling in normal group, fasted for 48 h but free access to water with restriction of rats onto the fixationframe for cooling in 4℃ for 4 h, so to cause stress injury of gastric mucosal membrane in I group and fed with3 mL of collagen solution 30min before injury in P group in addition to the procedures in I grobp. Gastricmucosal potential difference, blood flow volume, content of nitrite (NO2-) and hydrogen ion concentration(H+ ) in gastric juice were determined under aneasthesia at 48 h after fast in N group and at 4 h after injuryin I and P groups to evaluate the degree of injury (injury index).RESULTS Gastric mucosal potential difference was 22.10±5.27 in N group and 11.46±5.25 in I groupwith obvious difference (P<0.01), but 16.98±4.84 in P group which was remarkably improved whencompared to that in I group. Gastric mucosal blood flow volume was 23.65±10.65 in I group and 57.20±11.75 in N group with evident difference (P<0.01), but 37.49±5.87 in P group with sound effects incontrast to that in I group (P<0.01). Gastric injury index was 18.40±8.35 in I group and 7.9±2.13 in Pgroup with significant difference (P<0.01). Hydrogenion concentration in gastric juice was 118.0±41.2mmol/L in N group, 186.9±74.7 mmol/L in I group and 96.4±57.2 mmol/L in P group with prominentdifference (P< 0.01 ) between those in I and P group. Gastric mucosal nitrite concentration was 1.15±0.46in N group, 0.69±0.15 in I group and 1.04±0.44 in P group with obvious differences between N and Igroups (P<0.01) and between I and P group (P<0.01).CONCLUSION Ischemic and hypoxic injury of gastric mucosal due to low blood perfusion during restrictionand cooling injury at 4℃ was supposed to be an important factor in inducing gastric mucosal stress injury. Butcollagen solution could maintain the integrity of gastric mucosal barrier, buffer gastric acid, promotethrombocytic agglutination and ameliorate direct injury to gastric mucosa caused by various factors.

神经生长因子和碱性成纤维细胞生长因子联用治疗坐骨神经损伤实验研究

AIM:To explore the co- effect of nerve growth factor (NGF) and basic fibroblast growth factor (bFGF) on the sciatic nerve after injury. METHODS: 96 rats were divided into normal saline group, NGF group, bFGF group and NGF+ bFGF group. Sciatic nerve function index (SFI), nerve conduction velocity, regeneration axon counting were detected in the 3 rd, 6 th, 9 th, 12 th week postinjury. RESULTS:The end of SFI, nerve conduction velocity, regeneration axon counting in NGF+ bFGF group were higher than those in the other groups. CONCLUSION:The co- effect of NGF and bFGF on sciatic nerve is better than the effect of NGF or bFGF alone.

Objective To discuss a simple, safe and effective management for the the posterior urethral injury after pelvic fracture.Methods: The patients were treated by the simplified urethral realignment with traction; in the operation, the two -way catheter with an inner metal frame was implanted by the guidance of forefinger. After the operation, urethral dilation was processed regularly. Results 41 cases have been followed up and 36 cases can midurate normally, so the curative rate was 87. 8%. ln those, impotence occurred 3 cases. Conclusions The proper application of the urethral realignment with tradion followed by regular urethral dilation has an effecf on the patients of the the posterior urethral injury in pelvic fracture.

New Hope in Promoting Central Neural Regeneration

MRI 诊断半月板损伤对关节镜术及预后的价值

MRI diagnosing meniscus has hign accuracy,but there exist false positive and negative results.Our hospital collect fifty case patient,and do research on control class study by arthroscopy.We give the patient careful physical examination before operation,We want to know wether these methods have significance for diagnosis and therapy and prognosis of meniscus injury and follow visit prognosis of patient with grade one and two signals.

钢管舞运动损伤调查研究

通过问卷等方法对国家队20名女子钢管舞者进行了运动损伤类型、损伤原因调查，结果表明：女子钢管舞者运动运动损伤部位±次为大腿内侧、小腿内侧、大腿后肌群拉伤、颈椎劳损、踝部骨关节病、腰肌劳损。损伤类型包括胼胝、擦伤、延迟性肌肉酸痛以及瘀伤；大部分损伤部位在下肢；主要为慢性损伤。