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Atopic dermatitis.
影响因子:202.731 DOI:10.1016/S0140-6736(20)31286-1
作者: Langan SM,Irvine AD,Weidinger S 发表时间:2020-08-28 09:44:31
keywords: Langan SMIrvine ADWeidinger S
关键词:
Abstract
:Atopic dermatitis is a common inflammatory skin disorder characterised by recurrent eczematous lesions and intense itch. The disorder affects people of all ages and ethnicities, has a substantial psychosocial impact on patients and relatives, and is the leading cause of the global burden from skin disease. Atopic dermatitis is associated with increased risk of multiple comorbidities, including food allergy, asthma, allergic rhinitis, and mental health disorders. The pathophysiology is complex and involves a strong genetic predisposition, epidermal dysfunction, and T-cell driven inflammation. Although type-2 mechanisms are dominant, there is increasing evidence that the disorder involves multiple immune pathways. Currently, there is no cure, but increasing numbers of innovative and targeted therapies hold promise for achieving disease control, including in patients with recalcitrant disease. We summarise and discuss advances in our understanding of the disease and their implications for prevention, management, and future research.
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英文简介 : The Lancet is the world''s leading independent general medical journal. The journal''s coverage is international in focus and extends to all aspects of human health.The Lancet is published weekly from editorial offices in London and New York. It aims to publish the best original primary research papers, and review articles of the highest standard. The Lancet is stringently edited and peer-reviewed to ensure the scientific merit and clinical relevance of its diverse content. Drawing on an international network of advisers and contributors, The Lancet meets the needs of physicians by adding to their clinical knowledge and alerting them to current issues affecting the practise of medicine world wide. The blend of challenging editorials, signed commentaries, original research, commissioned reviews, an international news section, and the views of readers in the letters pages make The Lancet an essential weekly read for physicians all over the world.The Lancet is available by personal subscription to individual physicians. It is also available by subscription to institutions, libraries, and biomedical companies.Visit The Lancet''s World Wide Web site to find out more - http://www.thelancet.com
中文简介 : (来自Google、百度翻译) 《柳叶刀》是世界领先的独立医学杂志。该杂志的报道是国际性的,涵盖了人类健康的各个方面。《柳叶刀》每周在伦敦和纽约的编辑部出版。它的目标是发表最好的原创初级研究论文,并审查最高标准的文章。《柳叶刀》经过严格编辑和同行评审,以确保其多样化内容的科学价值和临床相关性。《柳叶刀》利用顾问和捐助者的国际网络,通过增加医生的临床知识和提醒他们注意影响全世界医学实践的当前问题,满足了医生的需要。具有挑战性的社论、署名评论、原创研究、委托撰写的评论、一个国际新闻版块,以及读者来信页面的观点,使《柳叶刀》成为世界各地医生每周必读的杂志。《柳叶刀》可由个人医生订阅。它也可通过订阅机构,图书馆和生物医药公司。请访问《柳叶刀》的全球网站http://www.thelancet.com了解更多信息
CIRCULATION RESEARCH 期刊中科院评价数据
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大类(学科) 小类(学科) 学科排名
医学

MEDICINE, GENERAL & INTERNAL (医学:内科)

2/155
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总被引频次 :247292

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