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您当前的位置:   首页  >  SCI文献  >  Pelvic sentinel lymph node biopsy in endometrial cancer-a simplified algorithm based on histology and lymphatic anatomy.

Pelvic sentinel lymph node biopsy in endometrial cancer-a simplified algorithm based on histology and lymphatic anatomy.
影响因子：4.661 DOI：10.1136/ijgc-2019-000935
作者： Bollino M,Geppert B,Lönnerfors C,Falconer H,Salehi S,Persson J 发表时间：2020-08-28 08:20:26
from：《INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER》
keywords： Bollino MGeppert BLönnerfors CFalconer HSalehi SPersson J
关键词：
Abstract
OBJECTIVE:To achieve the full potential of sentinel lymph node (SLN) detection in endometrial cancer, both presumed low- and high-risk groups should be included. Perioperative resource use and complications should be minimized. Knowledge on distribution and common anatomical sites for metastatic SLNs may contribute to optimizing the concept while maintaining sensitivity. Proceeding from previous studies, simplified algorithms based on histology and lymphatic anatomy are proposed. METHODS:Data on mapping rates and locations of pelvic SLNs (metastatic and non-metastatic) from two previous prospective SLN studies in women with endometrial cancer were retrieved. Cervically injected indocyanine green was used as a tracer and an ipsilateral re-injection was performed in case of non-display of the upper and/or lower paracervical pathways. A systematic surgical algorithm was followed with clearly defined SLNs depicted on an anatomical chart. In high-risk endometrial cancer patients, removal of SLNs was followed by a pelvic and para-aortic lymphadenectomy. RESULTS:423 study records were analyzed. The bilateral mapping rates of the upper and lower paracervical pathways were 88.9% and 39.7%, respectively. 72% of all SLNs were typically positioned along the upper paracervical pathway (interiliac and/or proximal obturator fossa) and 71 of 75 (94.6%) of pelvic node positive women had at least one metastatic SLN at either of these positions. Women with grade 1-2 endometroid cancers (n=275) had no isolated metastases along the lower paracervical pathway compared with two women with high-risk histologies (n=148). CONCLUSION:SLNs along the upper paracervical pathway should be identified in all endometrial cancer histological subtypes; removal of nodes at defined typical positions along the upper paracervical pathway may replace a site-specific lymphadenectomy in case of non-mapping despite tracer re-injection. Detection of SLNs along the lower paracervical pathway can be restricted to high-risk histologies and a full pre-sacral lymphadenectomy should be performed in case of non-display.
摘 要
期刊介绍
《INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER》 (点击进入期刊详情)
英文简介 : Official Journal of the International Gynecologic Cancer Society. International Journal of Gynecological Cancer presents papers from throughout the global community of researchers covering many topics including: basic science; epidemiology; diagnostic techniques; surgery; radiotherapy; chemotherapy; pathology; experimental studies The Journal allows you to call on a roster of international experts for the latest research, advice, and knowledge in order to provide the best treatment for your patients.
中文简介 : （来自Google、百度翻译） 国际妇科癌症学会官方期刊。《国际妇科癌症杂志》发表了来自全球研究人员的论文，涵盖许多主题，包括:基础科学;流行病学;诊断技术;手术;放射治疗;化疗;病理学;《实验研究》杂志允许您向国际专家咨询最新的研究、建议和知识，以便为您的患者提供最佳的治疗。Official Journal of the International Gynecologic Cancer Society. International Journal of Gynecological Cancer presents papers from throughout the global community of researchers covering many topics including: basic science; epidemiology; diagnostic techniques; surgery; radiotherapy; chemotherapy; pathology; experimental studies The Journal allows you to call on a roster of international experts for the latest research, advice, and knowledge in order to provide the best treatment for your patients.
CIRCULATION RESEARCH 期刊中科院评价数据
新中科院分区
大类(学科) 小类(学科) 学科排名
医学

OBSTETRICS & GYNECOLOGY (妇产科学)

ONCOLOGY (肿瘤学)

35/82
167/223
新发布的期刊年发文量
年度总发文量 年度论文发表量 年度综述发表量
277 253 24

总被引频次 :6622

特征因子 : 0.009840

影响因子趋势图

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