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Maternal Gestational Diabetes and Type 2 Diabetes During Pregnancy and Risk of Childhood Asthma in Offspring.
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Abstract:
OBJECTIVE:To examine maternal preexisting type 2 diabetes (T2D) and gestational diabetes mellitus (GDM) on risk of childhood asthma. STUDY DESIGN:This retrospective birth cohort study included 97 554 singletons born in 2007-2011 within hospitals from a single integrated healthcare system. Children were prospectively followed from age 5 until December 31, 2017, using electronic medical records. Relative risks of childhood asthma associated with maternal diabetes in utero were estimated by hazard ratios using Cox regression adjusting for potential confounders. RESULTS:There were 3119 children (3.2%) who were exposed to preexisting T2D and 9836 (10.1%) to GDM. Among mothers with GDM, 3380 (34.4%) were dispensed antidiabetic medication during pregnancy. During a median of 7.6 years (IQR, 6.3-9.0 years) after birth, 15 125 children (15.5%) were diagnosed with asthma after age 5. Maternal diabetes interacted with maternal asthma history to affect child's asthma risk (P = .05). Among children without maternal asthma (n = 89 487), the adjusted hazard ratios for childhood asthma were 1.21 (95% CI, 1.08-1.36; P < .001) for exposure to T2D, 1.12 (95% CI, 1.01-1.25; P = .04) for GDM requiring antidiabetic medications, and 1.01 (95% CI, 0.93-1.10; P = .82) for GDM not requiring medications compared with no diabetes during pregnancy. The corresponding hazard ratios were 1.53 (95% CI, 1.19-1.96; P < .001), 1.11 (95% CI, 0.65-1.46; P = .44), and 0.84 (95% CI, 0.66-1.08; P = .17) among children without maternal asthma (n = 8067). Gestational age at GDM diagnosis was not associated with childhood asthma (P = .27). CONCLUSIONS:The risk of childhood asthma was predominately observed for exposure to preexisting T2D, small for GDM requiring medication, and not increased for GDM not requiring medication during pregnancy, compared with no diabetes during pregnancy.
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JOURNAL OF PEDIATRICS
J PEDIATR-US
| 最新影响因子：6.314 | 期刊ISSN：0022-3476 | CiteScore：2.25 |
| 出版周期：Monthly | 是否OA：YES | 出版年份：1932 |
期刊官方网址：http://www.jpeds.com/
| 自引率：6.80% | 研究方向：医学-小儿科 |
| 出版地区：UNITED STATES |
SCI期刊coverage：Science Citation Index Expanded（科学引文索引扩展）
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JOURNAL OF PEDIATRICS 期刊简介
英文简介：
The Journal of Pediatrics is an international peer-reviewed journal that advances pediatric research and serves as a practical guide for pediatricians who manage health and diagnose and treat disorders in infants, children, and adolescents. The Journal publishes original work based on standards of excellence and expert review. The Journal seeks to publish high quality original articles that are immediately applicable to practice (basic science, translational research, evidence-based medicine), brief clinical and laboratory case reports, medical progress, expert commentary, grand rounds, insightful editorials, “classic” physical examinations, and novel insights into clinical and academic pediatric medicine related to every aspect of child health. Published monthly since 1932, The Journal of Pediatrics continues to promote the latest developments in pediatric medicine, child health, policy, and advocacy. Topics covered in The Journal of Pediatrics include, but are not limited to: General Pediatrics Pediatric Subspecialties Adolescent Medicine Allergy and Immunology Cardiology Critical Care Medicine Developmental-Behavioral Medicine Endocrinology Gastroenterology Hematology-Oncology Infectious Diseases Neonatal-Perinatal Medicine Nephrology Neurology Emergency Medicine Pulmonology Rheumatology Genetics Ethics Health Service Research Pediatric Hospitalist Medicine
中文简介：（来自Google、百度翻译）
《儿科杂志》是一份国际同行评审的杂志，它促进儿科研究，并作为儿科医生管理健康和诊断和治疗婴儿、儿童和青少年疾病的实用指南。该杂志根据优秀标准和专家评审发表原创作品。杂志试图发布高质量的原创文章,立即适用于实践(基础科学转化研究,循证医学),简短的临床和实验室案例报告,医学进步,专家评论,大轮,深刻的社论,小说“经典”体检,临床和学术见解儿科医学有关儿童健康的方方面面。自1932年以来，《儿科杂志》每月出版一次，继续推动儿科医学、儿童健康、政策和宣传方面的最新发展。 《儿科杂志》涵盖的主题包括但不限于: 一般儿科 儿科细分专业 青少年医学 过敏和免疫学 心脏病学 危重病医学 Developmental-Behavioral医学 内分泌学 胃肠病学 Hematology-Oncology 传染病 Neonatal-Perinatal医学 肾脏学 神经学 急诊医学 肺学 风湿病学 遗传学 道德 卫生服务研究 儿科Hospitalist医学
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JOURNAL OF PEDIATRICS 期刊中科院评价数据
最新中科院分区
| 大类(学科) | 小类(学科) | 学科排名 |
| 医学 |
PEDIATRICS (儿科) 2区 |
8/124 |
最新公布的期刊年发文量
| 年度总发文量 | 年度论文发表量 | 年度综述发表量 |
| 467 | 460 | 7 |
总被引频次：32002
特征因子：0.045030
影响因子趋势图
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JOURNAL OF PEDIATRICS 期刊CiteScore评价数据
最新CiteScore值
2.25
=
引文计数(2018)
文献(2015-2017)
=
5746次引用
2553篇文献
文献总数（2014-2016）：2553
被引比率：55%
SJR：1.522
SCLmago期刊等级衡量经过加权后的期刊受引用次数，引用次数的加权值由施引期刊的学科领域和声望(SJR)决定。
SNIP：1.471
每篇文章中来源出版物的标准化影响将实际受引用情况对照期刊所属学科领域中预期的受引用情况进行衡量。
CiteScore排名
| 序号 | 类别 | 排名 | 百分位 |
| 1 |
大类(学科)：Medicine
小类(学科)：Pediatrics, Perinatology and Child Health
|
#36/271
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CiteScore趋势图
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liting7111
研究方向：儿科
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liting7111
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在上周投稿，给了稿号450，照这样算，一年投稿2700篇，每年刊登501篇，接受率在5%，难度很大，这次估计要被拒了。2019-08-10 -
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