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Abstract:
Abstract Background Streptococcus suis is a zoonotic pathogen that causes serious systemic infections in pigs and occupation-related infections in humans who contact with pigs or pork products. In China, it has caused two outbreaks of human infection and surveillance for S.suis has been ongoing since last time. Case presentation Two cases of meningitis and sepsis caused by S. suis were reported in this study. Both patients work in relation to the pork trade, a risk factor for S. suis infection. The outcome was favorable after a prolonged ceftriaxone therapy but one patient was left with mild hearing loss. Two isolates were identified as sequencing type (ST) 7, S. suis serotype 2 (SS2), which is one the most prevalent and cause two outbreaks in China. Whole-genome sequencing (WGS) revealed that a high degree identity was noted in the genome organizations and sequences between two sporadic ST7 SS2 isolates in this study and representative epidemic virulent isolates. Major differences among them are two sporadic ST7 SS2 isolates lacked a virulence factor called agglutinin receptor and an 89 K pathogenicity island (PAI), which plays important role in the pathogenesis of streptococcal toxic shock syndrome (STSS). A summary about STs of human infection with S. suis in China was completed. The result showed ST1 and ST7 were still the major STs and several novel STs were successfully discovered in different provinces. Conclusions Our results enhanced the understanding of the ability to cause life-threatening infections in humans and the distribution and evolution of the S. suis in China.
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最新影响因子:3.667 | 期刊ISSN:1471-2334 | CiteScore:2.86 |
出版周期:Irregular | 是否OA:YES | 出版年份:2001 |
自引率:4.70% | 研究方向:医学-传染病学 |
出版地区:ENGLAND |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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Published by BioMed Central. ISSN: 1471-2334. BMC Infectious Diseases publishes original research articles in all aspects of the prevention, diagnosis and management of infectious and sexually transmitted diseases, as well as related molecular genetics, pathophysiology, and epidemiology.
由生物医学中心出版。ISSN: 1471 - 2334。 BMC传染病在传染病和性传播疾病的预防、诊断和管理,以及相关的分子遗传学、病理生理学和流行病学的所有方面发表原创研究文章。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
INFECTIOUS DISEASES (传染病学) 3区 |
44/88 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
794 | 746 | 48 |
引文计数(2018)
文献(2015-2017)
6069次引用
2124篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Medicine
小类(学科):Infectious Diseases
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#64/266
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研究方向:免疫
审稿时间: 6个月内 接受率: 比较困难(25%命中)
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接受率: 一般容易(75%命中)
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研究方向:感染
审稿时间: 3个月内 接受率: 中等(50%命中)
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研究方向:肝病 免疫
审稿时间: 2个月内 接受率: 中等(50%命中)
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研究方向:感染与免疫
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研究方向:肺损伤 缺血缺氧脑病
审稿时间: 2个月内 接受率: 一般容易(75%命中)
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审稿时间: 3个月内 接受率: 中等(50%命中)
影响因子:2.566
ISSN:0739-7240
研究方向:农林科学-奶制品与动物科学
影响因子:6.497
ISSN:1172-7047
研究方向:医学-精神病学
影响因子:1.297
ISSN:0028-2804
研究方向:医学-精神病学
影响因子:4.604
ISSN:1092-8529
研究方向:医学-精神病学
影响因子:5.345
ISSN:1398-5647
研究方向:医学-精神病学
影响因子:3.492
ISSN:1540-2002
研究方向:CLINICAL NEUROLOGY-PSYCHIATRY
影响因子:4.562
ISSN:0269-8811
研究方向:医学-精神病学
影响因子:6.533
ISSN:0165-0327
研究方向:医学-精神病学
影响因子:5.415
ISSN:0924-977X
研究方向:医学-精神病学
发表一篇学和医学成像类SCI论文
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