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Association Between Cardiovascular Disease and Long-term Exposure to Air Pollution With the Risk of Dementia.
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Abstract:
Importance:Emerging yet contrasting evidence associates air pollution with incident dementia, and the potential role of cardiovascular disease (CVD) in this association is unclear. Objective:To investigate the association between long-term exposure to air pollution and dementia and to assess the role of CVD in that association. Design, Setting, and Participants:Data for this cohort study were extracted from the ongoing Swedish National Study on Aging and Care in Kungsholmen (SNAC-K), a longitudinal population-based study with baseline assessments from March 21, 2001, through August 30, 2004. Of the 5111 randomly selected residents in the Kungsholmen district of Stockholm 60 years or older and living at home or in institutions, 521 were not eligible (eg, due to death before the start of the study or no contact information). Among the remaining 4590 individuals, 3363 (73.3%) were assessed. For the current analysis, 2927 participants who did not have dementia at baseline were examined, with follow-up to 2013 (mean [SD] follow-up time, 6.01 [2.56] years). Follow-up was completed February 18, 2013, and data were analyzed from June 26, 2018, through June 20, 2019. Exposures:Two major air pollutants (particulate matter ≤2.5 μm [PM2.5] and nitrogen oxide [NOx]) were assessed yearly from 1990, using dispersion models for outdoor levels at residential addresses. Main Outcomes and Measures:The hazard of dementia was estimated using Cox proportional hazards regression models. The potential of CVD (ie, atrial fibrillation, ischemic heart disease, heart failure, and stroke) to modify and mediate the association between long-term exposure to air pollution and dementia was tested using stratified analyses and generalized structural equation modeling. Results:At baseline, the mean (SD) age of the 2927 participants was 74.1 (10.7) years, and 1845 (63.0%) were female. Three hundred sixty-four participants with incident dementia were identified. The hazard of dementia increased by as much as 50% per interquartile range difference in mean pollutant levels during the previous 5 years at the residential address (hazard ratio [HR] for difference of 0.88 μg/m3 PM2.5, 1.54 [95% CI, 1.33-1.78]; HR for difference of 8.35 μg/m3 NOx, 1.14 [95% CI, 1.01-1.29]). Heart failure (HR for PM2.5, 1.93 [95% CI, 1.54-2.43]; HR for NOx, 1.43 [95% CI, 1.17-1.75]) and ischemic heart disease (HR for PM2.5, 1.67 [95% CI, 1.32-2.12]; HR for NOx, 1.36 [95% CI, 1.07-1.71]) enhanced the dementia risk, whereas stroke appeared to be the most important intermediate condition, explaining 49.4% of air pollution-related dementia cases. Conclusions and Relevance:This study found that long-term exposure to air pollution was associated with a higher risk of dementia. Heart failure and ischemic heart disease appeared to enhance the association between air pollution and dementia, whereas stroke seemed to be an important intermediate condition between the association of air pollution exposure with dementia.
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JAMA Neurology
JAMA NEUROL
| 最新影响因子：29.907 | 期刊ISSN：2168-6149 | CiteScore：5.14 |
| 出版周期： | 是否OA：YES | 出版年份：0 |
| 自引率：2.70% | 研究方向：CLINICAL NEUROLOGY- |
| 出版地区：UNITED STATES |
SCI期刊coverage：Science Citation Index Expanded（科学引文索引扩展）
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JAMA Neurology 期刊简介
英文简介：
JAMA Neurology is an international peer-reviewed journal for physicians caring for people with neurologic disorders and those interested in the structure and function of the normal and diseased nervous system. The Archives of Neurology & Psychiatry began publication in 1919 and, in 1959, became 2 separate journals: Archives of Neurology and Archives of General Psychiatry. In 2013, their names changed to JAMA Neurology and JAMA Psychiatry, respectively. JAMA Neurology is a member of the JAMA Network family of journals, which includes JAMA, 11 JAMA Network specialty journals, and JAMA Network Open. Journal Frequency and Access. JAMA Neurology is published online weekly, every Monday, and in 12 print/online issues a year. The journal receives over 2.8 million online visits annually, and more than 3.7 million article views and downloads. Without any author fees, all research articles are made free access online 12 months after publication on the website. In addition, the online version is freely available or nearly so to institutions in developing countries through the World Health Organization's HINARI program.
中文简介：（来自Google、百度翻译）
《美国医学会神经病学杂志》是一份国际同行评审的期刊，为那些关心神经疾病患者以及那些对正常和病变神经系统的结构和功能感兴趣的医生提供服务。《神经病学与精神病学档案》于1919年开始出版，1959年成为两种独立的期刊:《神经病学档案》和《普通精神病学档案》。2013年，他们分别更名为《美国医学会神经病学分会》(JAMA Neurology)和《美国医学会精神病学分会》(JAMA Psychiatry)。JAMA神经学是JAMA网络期刊家族的一员，包括JAMA、11种JAMA网络专业期刊和JAMA网络开放期刊。 期刊频率和访问。《美国医学会神经病学杂志》每周一在线出版，每年出版12期。《华尔街日报》每年的在线访问量超过280万次，文章浏览量和下载量超过370万次。所有研究论文在网站发表12个月后，均可免费在线阅读，不收取任何作者费用。此外，通过世界卫生组织(World Health Organization)的HINARI项目，发展中国家的机构几乎可以免费获得在线版本。
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JAMA Neurology 期刊中科院评价数据
最新中科院分区
| 大类(学科) | 小类(学科) | 学科排名 |
| 医学 |
CLINICAL NEUROLOGY (临床神经病学) 1区 |
5/197 |
最新公布的期刊年发文量
| 年度总发文量 | 年度论文发表量 | 年度综述发表量 |
| 133 | 122 | 11 |
总被引频次：8683
特征因子：0.042040
影响因子趋势图
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JAMA Neurology 期刊CiteScore评价数据
最新CiteScore值
5.14
=
引文计数(2018)
文献(2015-2017)
=
5235次引用
1018篇文献
文献总数（2014-2016）：1018
被引比率：61%
SJR：4.925
SCLmago期刊等级衡量经过加权后的期刊受引用次数，引用次数的加权值由施引期刊的学科领域和声望(SJR)决定。
SNIP：2.691
每篇文章中来源出版物的标准化影响将实际受引用情况对照期刊所属学科领域中预期的受引用情况进行衡量。
CiteScore排名
| 序号 | 类别 | 排名 | 百分位 |
| 1 |
大类(学科)：Medicine
小类(学科)：Neurology (clinical)
|
#17/336
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CiteScore趋势图
Scopus涵盖范围
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最新评论(不代表本站观点)
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liting7111
研究方向：神经病学 卒中 脑血管疾病
接受率： 中等（50%命中）
明年有望IF7分左右，也算是顶级期刊，有望超过Stroke，neurology等老牌杂志2020-06-26 -
liting7111
非常高水平的神经病学杂志2020-03-20 -
liting7111
研究方向：神经病学 癫痫 卒中
审稿时间： 2个月内 接受率： 比较困难（25%命中）
算是新刊，所以影响因子很高2020-02-09 -
liting7111
研究方向：神经肿瘤
审稿时间： 2个月内 接受率： 比较困难（25%命中）
审稿速度一般，一般在2个月左右，一审时间短一点，因为是小修，所以不需要外审。发了催稿信，回复说正在仔细审核，第二天就给了结果。2020-02-06 -
liting7111
研究方向：脑卒中 神经影像
接受率： 比较困难（25%命中）
14年12月投了一篇clinical image，两周后给回复，小修修回后接收，大牌杂志审稿很快！2019-12-07 -
liting7111
接受率： 非常困难（几乎不命中）s
JAMA Neurology is an international peer-reviewed journal published in print 12 times a year and online every Monday. The journal began publishing as Archives of Neurology & Psychiatry in 1919 and, in 1959, became 2 separate journals: Archives of Neurology and Archives of General Psychiatry. The journal publishes occasional theme issues on topics such as cerebrovascular diseases, epilepsy, neuromuscular diseases, neoplasms, multiple sclerosis, movement disorders, Alzheimer disease, neurotherapeutics, genetics, sleep disorders, headache syndromes, emergency neurology, neuro-ophthalmology, neuro-otology, neurodegenerative diseases, ethical issues, and neurobiotechnology. The acceptance rate is 16%. The average time from submission to acceptance is 48 days; from acceptance to publication is 6 months.2019-12-02 -
liting7111
谁来说说这杂志明年多少分？2019-02-09
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