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Assessment of out-of-field doses in radiotherapy treatments of paediatric patients using Monte Carlo methods and measurements.

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Abstract:

PURPOSE:To assess out-of-field doses in radiotherapy treatments of paediatric patients, using Monte Carlo methods to implement a new model of the linear accelerator validated against measurements and developing a voxelized anthropomorphic paediatric phantom. METHODS:CT images of a physical anthropomorphic paediatric phantom were acquired and a dosimetric planning using a TPS was obtained. The CT images were used to perform the voxelization of the physical phantom using the ImageJ software and later implemented in MCNP. In order to validate the Monte Carlo model, dose measurements of the 6 MV beam and Linac with 120 MLC were made in a clinical setting, using ionization chambers and a water phantom. Afterwards TLD measurements in the physical anthropomorphic phantom were performed in order to assess the out-of-field doses in the eyes, thyroid, c-spine, heart and lungs. RESULTS:The Monte Carlo model was validated for in-field and out-of-field doses with average relative differences below 3%. The average relative differences between TLD measurements and Monte Carlo is 14,3% whilst the average relative differences between TLD and TPS is 55,8%. Moreover, organs up to 22.5 cm from PTV center show TLD and MCNP6 relative differences and TLD and TPS relative differences up to 21.2% and 92.0%, respectively. CONCLUSIONS:Our study provides a novel model that could be used in clinical research, namely in dose evaluation outside the treatment fields. This is particularly relevant, especially in pediatric patients, for studying new radiotherapy treatment techniques, since it can be used to estimate the development of secondary tumours.

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Physica Medica-European Journal of Medical Physics

PHYS MEDICA
最新影响因子:2.485 期刊ISSN:1120-1797 CiteScore:
出版周期:Quarterly 是否OA:YES 出版年份:1987

期刊官方网址:http://www.journals.elsevier.com/physica-medica/

期刊投稿地址:http://ees.elsevier.com/ejmp/default.asp?pg=preRegistration.asp

自引率:33.50% 研究方向:生物-生物物理
出版地区:ITALY

SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)

NCBI查询:PubMed Central (PMC)链接全文检索(pubmed central)

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Physica Medica-European Journal of Medical Physics 期刊简介

英文简介:

Physica Medica, European Journal of Medical Physics, publishing with Elsevier from 2007, provides an international forum for research and reviews on the following main topics: Medical Imaging Radiation Therapy Radiation Protection Measuring Systems and Signal Processing Education and training in Medical Physics Professional issues in Medical Physics. Contributions on other topics related to Applications of Physics to Biology and Medicine and in particular related to new emerging fields such as Molecular Imaging, Hadrontherapy, System biology, Nanoparticles and Nanotechnologies, etc. are strongly encouraged. Benefits to authors We also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services. Please see our Guide for Authors for information on article submission. If you require any further information or help, please visit our Support Center

中文简介:(来自Google、百度翻译)

欧洲医学物理杂志Physica Medica与爱思唯尔合作出版于2007年,为以下主要课题的研究和评论提供了一个国际论坛: 医学成像 放射治疗 辐射防护 测量系统和信号处理 医学物理教育与训练 医学物理学的专业问题。 强烈鼓励在与物理在生物学和医学上的应用有关的其他主题,特别是与分子成像、强子治疗、系统生物学、纳米颗粒和纳米技术等新兴领域有关的其他主题上作出贡献。 好处的作者 我们也提供许多作者的利益,如免费的pdf,自由的版权政策,特别折扣的爱思唯尔出版物和更多。请按此浏览更多有关作者服务的资料。 有关文章提交的信息,请参阅我们的作者指南。如果您需要进一步的信息或帮助,请访问我们的支持中心

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Physica Medica-European Journal of Medical Physics 期刊中科院评价数据

最新中科院分区

大类(学科) 小类(学科) 学科排名
医学 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING(放射学,核医学和医学成像) 3区
57/129

最新公布的期刊年发文量

年度总发文量 年度论文发表量 年度综述发表量
265 240 25
总被引频次:2641
特征因子:0.006270

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Physica Medica-European Journal of Medical Physics 期刊CiteScore评价数据

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SCLmago期刊等级衡量经过加权后的期刊受引用次数,引用次数的加权值由施引期刊的学科领域和声望(SJR)决定。
SNIP:
每篇文章中来源出版物的标准化影响将实际受引用情况对照期刊所属学科领域中预期的受引用情况进行衡量。

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