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Abstract:
OBJECTIVE:To assess whether quantitative changes in the meniscus predict progression from early knee osteoarthritis (KOA) to knee replacement (KR). METHODS:A nested case-control study was conducted among Osteoarthritis Initiative participants: All 35 case knees with baseline Kellgren-Lawrence-Grade (KLG) ≤2 that had KR between 36-60 months were matched 1:1 by age, sex, and baseline KLG to 35 control knees, without subsequent KR. Quantitative 3D medial meniscus position and morphological measures were determined from MRI at the visit just before KR (T0 ) and two years before (T-2 ). Paired t-tests and case-control odds ratios (OR, standardized per SD of change in controls) were used to compare changes between groups. RESULTS:Cases (52% women; age 65±7y; BMI 30±4kg/m2 ; KLG0/1/2: 5/8/22) and controls (52% women; age 64±7y; BMI 30±5kg/m2 ; KLG0/1/2: 9/4/22) were similar. Compared to control knees, KR case knees displayed longitudinal changes, specifically, a decrease in tibial plateau coverage, an increase in meniscal extrusion, and a decrease in meniscal width. The odds for KR increased with greater reduction in percent tibial plateau coverage (OR: 2.28, 95%CI [1.43; 3.64]), greater increase in maximal extrusion (1.40 [1.12; 1.75]), and greater reduction of mean meniscal width (2.01 [1.23; 3.26]). The odds for KR increased with medial compartment cartilage thickness loss (OR: 2.86 [1.51; 5.41]) for comparison. CONCLUSIONS:Quantitative measures of meniscal position and morphology are associated with subsequent KR in knees with rapidly progressing KOA. These findings show that structural changes of the meniscus are related to an important clinical and economic outcome of KOA.
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最新影响因子:5.178 | 期刊ISSN:2151-464X | CiteScore:N/A |
出版周期: | 是否OA:YES | 出版年份:2010 |
期刊官方网址:http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)2151-4658
自引率:5.60% | 研究方向:RHEUMATOLOGY- |
出版地区:UNITED STATES |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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Arthritis Care & Research, an official journal of the American College of Rheumatology and the Association of Rheumatology Health Professionals, publishes original research, review articles, and editorials that promote excellence in the clinical practice of rheumatology. Relevant to the care of individuals with rheumatic diseases, major topics are evidence-based practice studies, clinical problems, practice guidelines, educational, social, and public health issues, health economics, health care policy, and future trends in rheumatology practice.
关节炎护理与研究,美国风湿病学院和风湿病健康专业人员协会的官方杂志,出版了促进风湿病临床实践卓越的原始研究、评论文章和社论。与风湿病患者的护理相关,主要主题是循证实践研究、临床问题、实践指南、教育、社会和公共卫生问题、卫生经济学、卫生保健政策以及风湿病实践的未来趋势。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
RHEUMATOLOGY (风湿病学) 3区 |
9/30 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
236 | 225 | 11 |
引文计数(2018)
文献(2015-2017)
N/A次引用
N/A篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Medicine
小类(学科):Rheumatology
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研究方向:关节炎 护理
接受率: 比较困难(25%命中)
影响因子:2.395
ISSN:0899-8493
研究方向:医学-生理学
影响因子:11.067
ISSN:1077-5552
研究方向:医学-免疫学
影响因子:1.479
ISSN:1080-6032
研究方向:医学-公共卫生、环境卫生与职业卫生
影响因子:0.722
ISSN:0025-7826
研究方向:医学-医学:内科
影响因子:2.896
ISSN:1476-3141
研究方向:医学-工程:生物医学
影响因子:2.034
ISSN:0268-0033
研究方向:医学-工程:生物医学
影响因子:1.606
ISSN:1065-8483
研究方向:医学-工程:生物医学
影响因子:0.729
ISSN:0959-3020
研究方向:医学-工程:生物医学
影响因子:2.218
ISSN:1934-1482
研究方向:REHABILITATION-SPORT SCIENCES
ARTHRITIS CARE & RESEARCH 投稿经验
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