发表一篇学和医学成像类SCI论文
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Abstract:
The functional loss of adult stem cells is a major cause of aging and age-related diseases. Changes in the stem cell niche, increased energy metabolic rate, and accumulation of cell damage severely affect the function and regenerative capacity of stem cells. Reducing the cellular damage and maintaining a pristine stem cell niche by regulating the energy metabolic pathways could be ideal for the proper functioning of stem cells and tissue homeostasis. Numerous studies point out that caloric restriction (CR) has beneficiary effects on stem cell maintenance and tissue regeneration. Recent researches indicate the preventive nature of calorie restriction in stem cells by modulating the stem cell niche through the reduction of energy metabolism and eventually decrease stem cell damage. In this review, we have focused on the general stimuli of stem cell aging, particularly the energy metabolism as an intrinsic influence and stem cell niche as an extrinsic influence in different adult stem cells. Further, we discussed the mechanism behind CR in different adult stem cells and their niche. Finally, we conclude on how CR can enhance the stem cell function and tissue homeostasis through the stem cells niche.
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最新影响因子:5.606 | 期刊ISSN:0946-2716 | CiteScore: |
出版周期:Monthly | 是否OA:YES | 出版年份:1995 |
自引率:2.00% | 研究方向:医学-医学:研究与实验 |
出版地区:GERMANY |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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Official Organ of the "German Working Group for Gene Therapy (DAG-GT)" Official Organ of the "Biomedical Research Association (KBF)" The employment of molecular biology and gene technology has enhanced the understanding of human diseases creating a new branch of research - that of "molecular medicine". The Journal of Molecular Medicine (JMM) publishes original papers rapid communications review articles and correspondence of the highest quality pertinent to all aspects of human biology and pathophysiology. The application of research involving gene technology gene therapy molecular structural analysis genetic epidemiology and molecular and clinical pharmacology has made unprecedented progress and precision possible in the understanding prevention diagnosis and treatment of human diseases. These areas of molecular medicine therefore will be given particular attention by the editorial board. Papers describing in vitro or animal studies will be accepted if they are relevant to normal or pathological human biology. Please include at the end of the acknowledgements a declaration that the experiments comply with the current laws of the country in which the experiments were performed.
“德国基因治疗工作组”官方机构“生物医学研究协会”官方机构分子生物学和基因技术的应用提高了对人类疾病的认识,创造了一个新的研究分支——“分子医学”。分子医学杂志(JMM)出版与人类生物学和病理生理学有关的所有方面的最高质量的原始论文、快速通讯评论文章和通信。基因技术、基因治疗、分子结构分析、遗传流行病学、分子与临床药理学等方面的研究应用,在认识人类疾病的预防、诊断与治疗方面,取得了前所未有的进展和精度。因此,分子医学的这些领域将受到编辑委员会的特别关注。描述体外或动物研究的论文,如果与正常或病理的人类生物学有关,将被接受。请在确认信的末尾附上一份声明,声明实验符合实验所在国的现行法律。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
GENETICS & HEREDITY (遗传学) 2区 MEDICINE, RESEARCH & EXPERIMENTAL (医学:研究与实验) 2区 |
29/171 20/133 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
117 | 80 | 37 |
引文计数(2018)
文献(2015-2017)
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研究方向:基因治疗 信号通路
审稿时间: 2个月内 接受率: 比较困难(25%命中)
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研究方向:自身免疫 分子机制 细胞凋亡
接受率: 中等(50%命中)
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研究方向:纤维化
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研究方向:肿瘤 靶向治疗 分子机制
审稿时间: 2个月内
影响因子:5.315
ISSN:0148-396X
研究方向:医学-临床神经学
影响因子:1.725
ISSN:0028-3770
研究方向:医学-临床神经学
影响因子:2.21
ISSN:1878-8750
研究方向:CLINICAL NEUROLOGY-SURGERY
影响因子:4.332
ISSN:1092-0684
研究方向:CLINICAL NEUROLOGY-SURGERY
影响因子:2.816
ISSN:0001-6268
研究方向:医学-临床神经学
影响因子:2.8
ISSN:0344-5607
研究方向:医学-临床神经学
影响因子:0.972
ISSN:1019-5149
研究方向:医学-临床神经学
影响因子:1.532
ISSN:0256-7040
研究方向:医学-临床神经学
影响因子:1.165
ISSN:1016-2291
研究方向:医学-临床神经学
发表一篇学和医学成像类SCI论文
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