发表一篇学和医学成像类SCI论文
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Abstract:
:Gastric cancer (GC) is the fifth most common cancer and the third leading cause of cancer-related mortality worldwide. Although multidisciplinary therapeutic strategies have improved treatment outcomes, the overall prognosis for patients with GC remains poor. Recently, immunotherapeutic agents targeting immunosuppressive proteins such as anti-programmed death-1 receptor and anti-programmed death ligand-1 (PD-L1) have emerged as effective treatment options for various cancers, including GC. In addition to their therapeutic role, the expression of PD-L1 has been used as a predictive biomarker for programmed death-1/PD-L1 treatment response and has been shown to have a prognostic role in certain cancers. This study aims to evaluate the expression of PD-L1 in GC samples from Jordanian patients and assess its prognostic role as well as its correlation with clinicopathologic variables. Gastrectomy samples from 96 patients diagnosed with gastric adenocarcinoma were included in the study. Immunohistochemistry assay was employed for PD-L1 testing, and the scoring was based on a combined positive score (CPS). It was found that 66.7% of the study samples were positive for PD-L1 (CPS≥1). The expression of PD-L1 was not significantly associated with any of the assessed clinicopathologic variables; however, it was found to be an independent favorable prognostic factor for overall survival (hazard ratio: 0.481; 95% confidence interval: 0.231-1.001; P=0.050).
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最新影响因子:1.992 | 期刊ISSN:1541-2016 | CiteScore:N/A |
出版周期: | 是否OA:YES | 出版年份:0 |
期刊官方网址:http://journals.lww.com/appliedimmunohist/pages/default.aspx
自引率:6.90% | 研究方向:ANATOMY & MORPHOLOGY-MEDICAL LABORATORY TECHNOLOGY |
出版地区:UNITED STATES |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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Applied Immunohistochemistry & Molecular Morphology covers newly developed identification and detection technologies, and their applications in research and diagnosis for the applied immunohistochemist & molecular Morphologist. Official Journal of the International Society for Immunohistochemisty and Molecular Morphology.
应用免疫组织化学和分子形态学包括最新开发的识别和检测技术,以及它们在应用免疫组织化学和分子形态学学家的研究和诊断中的应用。 国际免疫组织化学和分子形态学学会官方刊物。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
ANATOMY & MORPHOLOGY (解剖学与形态学) 3区 MEDICAL LABORATORY TECHNOLOGY (医学实验技术) 3区 PATHOLOGY (病理学) 3区 |
6/21 15/30 36/79 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
122 | 114 | 8 |
引文计数(2018)
文献(2015-2017)
N/A次引用
N/A篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Medicine
小类(学科):Anatomy
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2 |
大类(学科):Health Professions
小类(学科):Medical Laboratory Technology
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#0/28
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研究方向:医学 解剖学 形态学
审稿时间: 3个月内
影响因子:2.995
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研究方向:CLINICAL NEUROLOGY-RADIOLOGY, NUCLEAR MEDICINE & M
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研究方向:医学-核医学
影响因子:1.764
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研究方向:CLINICAL NEUROLOGY-RADIOLOGY, NUCLEAR MEDICINE & M
影响因子:4.966
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研究方向:医学-核医学
影响因子:3.005
ISSN:0301-0449
研究方向:医学-核医学
影响因子:2.396
ISSN:1793-5458
研究方向:OPTICS-RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGI
影响因子:3.632
ISSN:1084-9785
研究方向:医学-核医学
发表一篇学和医学成像类SCI论文
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