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Abstract:
:The effects of hippocampal (HPC) damage on rats' novel object preference (NOP) performance have been rather consistent, in that HPC lesions do not disrupt novelty preferences on the test. Conversely, there have been inconsistent findings regarding the effects of perirhinal cortex (PRh) lesions on rats' novel-object preferences. Given the concerns that have been raised regarding the internal validity of the NOP test, viz. that the magnitude of the novel-object preference does not necessarily reflect the strength in memory for an object, it could explain the discrepant findings. The goal of the present experiment was to examine the effects of PRh and HPC lesions on rats' object-recognition memory using a new modified delayed nonmatching-to-sample (mDNMS) task, as it circumvents the interpretational problems associated with the NOP test. Rats received PRh, HPC, or Sham lesions and were trained on the mDNMS task using a short delay (∼30 s). Both PRh and HPC rats acquired the task at the same rate as Sham rats, and reached a similar level of accuracy, indicating intact object-recognition. Thereafter, rats were tested on the NOP test using a 180-s delay. Rats with HPC lesions exhibited significant novel-object preferences, however, both the PRh and Sham rats failed to show a novelty preference. The discrepancy in both the PRh and Sham rats' performance on the mDNMS task and NOP test raises concerns regarding the internal validity of the NOP test, in that the magnitude of a rat's novel-object preference does not accurately reflect the persistence or accuracy of a rat's memory for the sample object.
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最新影响因子:3.352 | 期刊ISSN:0166-4328 | CiteScore:3.11 |
出版周期:Semimonthly | 是否OA:YES | 出版年份:1980 |
期刊官方网址:http://www.journals.elsevier.com/behavioural-brain-research/
期刊投稿地址:http://www.journals.elsevier.com/behavioural-brain-research/
自引率:5.40% | 研究方向:医学-行为科学 |
出版地区:NETHERLANDS |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
专业编辑在线一对一答疑及时解决您的问题
Behavioural Brain Research is an international, interdisciplinary journal dedicated to the publication of articles in the field of behavioural neuroscience, broadly defined. Contributions from the entire range of disciplines that comprise the neurosciences, behavioural sciences or cognitive sciences are appropriate, as long as the goal is to delineate the neural mechanisms underlying behaviour. Thus, studies may range from neurophysiological, neuroanatomical, neurochemical or neuropharmacological analysis of brain-behaviour relations, including the use of molecular genetic or behavioural genetic approaches, to studies that involve the use of brain imaging techniques, to neuroethological studies. Reports of original research, of major methodological advances, or of novel conceptual approaches are all encouraged. The journal will also consider critical reviews on selected topics.
《行为大脑研究》是一本国际性、跨学科的期刊,专门发表广义上的行为神经科学领域的文章。只要目标是描述行为背后的神经机制,来自包括神经科学、行为科学或认知科学在内的整个学科领域的贡献都是合适的。因此,研究范围可能从神经生理学、神经解剖学、神经化学或神经药理学分析脑行为关系,包括使用分子遗传学或行为遗传学方法,到涉及使用脑成像技术的研究,到神经行为学研究。报告的原始研究,主要方法的进步,或新的概念方法都是鼓励。该杂志还将考虑对选定主题的评论。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
BEHAVIORAL SCIENCES (行为科学) 3区 NEUROSCIENCES (神经科学) 3区 |
14/51 119/261 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
619 | 598 | 21 |
引文计数(2018)
文献(2015-2017)
5712次引用
1838篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Neuroscience
小类(学科):Behavioral Neuroscience
|
#11/68
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审稿时间: 2个月内 接受率: 一般容易(75%命中)
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研究方向:神经科学 认知科学 脑疾病
审稿时间: 2个月内 接受率: 中等(50%命中)
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研究方向:神经行为学 神经化学 代谢组学
接受率: 一般容易(75%命中)
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研究方向:神经医学 行为学 认知
接受率: 中等(50%命中)
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研究方向:神经科学 行为学 脑部疾病
审稿时间: 2个月内 接受率: 中等(50%命中)
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研究方向:生命科学 神经科学 认知科学 心理学
审稿时间: 1个月内
影响因子:1
ISSN:1758-1559
研究方向:农林科学-奶制品与动物科学
影响因子:1.656
ISSN:0009-4293
研究方向:化学-化学综合
影响因子:0.638
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研究方向:化学-化学综合
影响因子:0.354
ISSN:0001-9704
研究方向:化学-化学综合
影响因子:1.145
ISSN:0100-4042
研究方向:化学-化学综合
影响因子:4.036
ISSN:2046-2069
研究方向:chemical sciences-
影响因子:3.21
ISSN:2192-6506
研究方向:CHEMISTRY, MULTIDISCIPLINARY-
影响因子:2.63
ISSN:2191-1363
研究方向:CHEMISTRY, MULTIDISCIPLINARY-
影响因子:0.356
ISSN:0009-2770
研究方向:化学-化学综合
BEHAVIOURAL BRAIN RESEARCH 投稿经验
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