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Abstract:
:Massive obstetric haemorrhage (MOH) is a leading cause of maternal morbidity and mortality world-wide. Using the Australian and New Zealand Massive Transfusion Registry, we performed a bi-national cohort study of MOH defined as bleeding at ≥20 weeks' gestation or postpartum requiring ≥5 red blood cells (RBC) units within 4 h. Between 2008 and 2015, we identified 249 cases of MOH cases from 19 sites. Predominant causes of MOH were uterine atony (22%), placenta praevia (20%) and obstetric trauma (19%). Intensive care unit admission and/or hysterectomy occurred in 44% and 29% of cases, respectively. There were three deaths. Hypofibrinogenaemia (<2 g/l) occurred in 52% of cases in the first 24 h after massive transfusion commenced; of these cases, 74% received cryoprecipitate. Median values of other haemostatic tests were within accepted limits. Plasma, platelets or cryoprecipitate were transfused in 88%, 66% and 57% of cases, respectively. By multivariate regression, transfusion of ≥6 RBC units before the first cryoprecipitate (odds ratio [OR] 3·5, 95% CI: 1·7-7·2), placenta praevia (OR 7·2, 95% CI: 2·0-26·4) and emergency caesarean section (OR 4·9, 95% CI: 2·0-11·7) were independently associated with increased risk of hysterectomy. These findings confirm MOH as a major cause of maternal morbidity and mortality and indicate areas for practice improvement.
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最新影响因子:8.615 | 期刊ISSN:0007-1048 | CiteScore:3.43 |
出版周期:Semimonthly | 是否OA:YES | 出版年份:1955 |
期刊官方网址:http://onlinelibrary.wiley.com/journal/10.1111/%28ISSN%291365-2141
自引率:5.10% | 研究方向:医学-血液学 |
出版地区:ENGLAND |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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The Official Journal of the British Society for Haematology and the European Haematology Association. The British Journal of Haematology publishes original research papers in clinical, laboratory and experimental haematology. The Journal also features annotations, reviews, rapid papers of special scientific importance, short reports, Letters to the Editor and book reviews. In addition, the Journal publishes, in supplement form, abstracts of the meetings of the British Society for Haematology and the European Haematology Association.
英国血液学协会和欧洲血液学协会的官方期刊。英国血液学杂志在临床,实验室和实验血液学发表原始研究论文。该杂志还提供注释、评论、具有特殊科学重要性的快速论文、简短的报告、给编辑的信和书评。此外,该杂志以补充形式出版了英国血液学学会和欧洲血液学协会会议摘要。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
HEMATOLOGY (血液学) 2区 |
12/71 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
306 | 230 | 76 |
引文计数(2018)
文献(2015-2017)
5189次引用
1513篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Medicine
小类(学科):Hematology
|
#21/120
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研究方向:医学 血液学
审稿时间: 3个月内
liting7111
影响因子:5.576
ISSN:0885-3924
研究方向:医学-临床神经学
影响因子:6.005
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研究方向:医学-全科医学与补充医学
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影响因子:3.006
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研究方向:MEDICINE, GENERAL & INTERNAL-
影响因子:0.834
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研究方向:医学-医学:内科
影响因子:0.522
ISSN:1108-4189
研究方向:MEDICINE, GENERAL & INTERNAL-
影响因子:11.15
ISSN:1741-7015
研究方向:医学-医学:内科
BRITISH JOURNAL OF HAEMATOLOGY 投稿经验
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