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Abstract:
BACKGROUND:Pancreaticoduodenectomy (PD) is a standardized strategy for patients with middle and distal bile duct cancers. The aim of this study was to compare clinicopathological features of bile duct segmental resection (BDR) with PD in patients with extrahepatic cholangiocarcinoma. METHODS:Consecutive cases with extrahepatic cholangiocarcinoma who underwent BDR (n = 21) or PD (n = 84) with achievement of R0 or R1 resection in Kobe University Hospital between January 2000 and December 2016 were enrolled in the present study. RESULTS:Patients who underwent PD were significantly younger than those receiving BDR. The frequency of preoperative jaundice, biliary drainage and cholangitis was not significantly different between the two groups. The duration of surgery was longer and there was more intraoperative bleeding in the PD than in the BDR group (553 vs. 421 min, and 770 vs. 402 mL; both P<0.01). More major complications (>Clavien-Dindo IIIa) were observed in the PD group (46% vs. 10%, P<0.01). Postoperative hospital stay was also longer in that group (30 vs. 19 days, P = 0.02). Pathological assessment revealed that tumors were less advanced in the BDR group but the rate of lymph node metastasis was similar in both groups (33% in BDR and 48% in PD, P = 0.24). The rate of R0 resection was significantly higher in the PD group (80% vs. 38%, P<0.01). Adjuvant chemotherapy was more frequently administered to patients in the BDR group (62% vs. 38%, P = 0.04). Although 5-year overall survival rates were similar in both groups (44% for BDR and 51% for PD, P = 0.72), in patients with T1 and T2, the BDR group tended to have poorer prognosis (44% vs. 68% at 5-year, P = 0.09). CONCLUSIONS:BDR was comparable in prognosis to PD in middle bile duct cancer. Less invasiveness and lower morbidity of BDR justified this technique for selected patients in a poor general condition.
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最新影响因子:3.355 | 期刊ISSN:1499-3872 | CiteScore:1.65 |
出版周期:Bimonthly | 是否OA:YES | 出版年份:2002 |
期刊官方网址:http://www.hbpdint.com
自引率:5.70% | 研究方向:医学-胃肠肝病学 |
出版地区:PEOPLES R CHINA |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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Published by Zhejiang University School of Medicine, China. ISSN: 1499-3872. Hepatobiliary & Pancreatic Diseases International (HBPD INT) publishes peer-reviewed original papers, reviews and editorials concerned with clinical practice and research in the fields of hepatobiliary and pancreatic diseases. Papers cover the medical, surgical, radiological, pathological, biochemical, physiological and historical aspects of the subject areas under the headings Liver, Biliary, Pancreas, Transplantation, Research, Special Reports, Editorials, Review Articles, Brief Communications, Clinical Summary, Clinical Images and Case Reports. The journal also deals with the basic sciences and experimental work. All submitted papers are reviewed by at least two referees expert in the field of the submitted paper. For detailed instructions concerning the submission of manuscripts, please refer to the Instructions for Authors in each issue of the journal. HBPD INT is published bimonthly since 2007.
浙江大学医学院出版,中国。ISSN: 1499 - 3872。 国际肝胆胰疾病组织(HBPD INT)发表同行评议的原创性论文、评论和社论,涉及肝胆胰疾病领域的临床实践和研究。论文涵盖了医学、外科、放射学、病理学、生物化学、生理和历史方面的主题领域,标题下包括肝脏、胆道、胰腺、移植、研究、专题报道、社论、综述文章、简要交流、临床总结、临床影像和病例报告。该杂志还涉及基础科学和实验工作。所有提交的论文都由至少两名论文领域的评审专家评审。关于投稿的详细说明,请参阅每期期刊的作者说明。《HBPD国际》自2007年起双月刊出版。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
GASTROENTEROLOGY & HEPATOLOGY (胃肠肝病学) 4区 |
72/80 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
73 | 61 | 12 |
引文计数(2018)
文献(2015-2017)
459次引用
278篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Medicine
小类(学科):Hepatology
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#38/59
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2 |
大类(学科):Medicine
小类(学科):Gastroenterology
|
#65/128
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研究方向:肝胆胰 临床分析
审稿时间: 2个月内
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研究方向:肝胆胰
接受率: 非常困难(几乎不命中)
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研究方向:医学 胃肠肝病学
审稿时间: 2个月内
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影响因子:5.576
ISSN:0885-3924
研究方向:医学-临床神经学
影响因子:6.005
ISSN:0192-415X
研究方向:医学-全科医学与补充医学
影响因子:202.731
ISSN:0140-6736
研究方向:医学-医学:内科
影响因子:2.898
ISSN:1807-5932
研究方向:医学-医学:内科
影响因子:1.817
ISSN:0025-7974
研究方向:医学-医学:内科
影响因子:3.006
ISSN:2044-6055
研究方向:MEDICINE, GENERAL & INTERNAL-
影响因子:0.834
ISSN:0020-9554
研究方向:医学-医学:内科
影响因子:0.522
ISSN:1108-4189
研究方向:MEDICINE, GENERAL & INTERNAL-
影响因子:11.15
ISSN:1741-7015
研究方向:医学-医学:内科
Hepatobiliary & Pancreatic Diseases International 投稿经验
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