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Abstract:
PURPOSE:The C-reactive protein to albumin ratio (CAR) is a simple and useful score for predicting the outcomes of patients with various cancers. The aim of this study was to evaluate the CAR and short-term outcomes in oldest-old patients with colorectal cancer. METHODS:A total of 126 patients aged 85 years and older with colorectal cancer who underwent resection for primary colon cancer from April 2015 to December 2018 were included. The preoperative cutoff value of the CAR for predicting postoperative complications was 0.19 on receiver operating characteristic curve analysis. Clinical characteristics and inflammation-based scores were compared between patients with a high CAR (CAR ≥ 0.19, n = 44) and a low CAR (CAR < 0.19, n = 82). RESULTS:A high preoperative CAR level (≥ 0.19) was significantly associated with stoma construction (p = 0.004), blood loss (p = 0.003), postoperative complications (p = 0.016), and systemic inflammation marker levels, including a low neutrophil to lymphocyte ratio (p = 0.006), a low platelet to lymphocyte ratio (p = 0.005), a low prognostic nutritional index (p < 0.001), and a high modified Glasgow prognostic score (p < 0.001). On univariate and multivariate analyses, only the CAR was an independent predictor of postoperative complications (HR 2.864, p = 0.029). CONCLUSIONS:A high CAR was significantly associated with postoperative complications for oldest-old patients with colorectal cancer.
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最新影响因子:2.796 | 期刊ISSN:0179-1958 | CiteScore:1.6 |
出版周期:Bimonthly | 是否OA:YES | 出版年份:1986 |
自引率:6.60% | 研究方向:医学-外科 |
出版地区:GERMANY |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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The International Journal of Colorectal Disease aims to publish novel and state-of-the-art papers which deal with the physiology and pathophysiology of diseases involving the entire gastrointestinal tract. In addition to original research articles of high scientific quality reviews will be included and controversial issues from rapidly developing areas in gastroenterology and gastrointestinal surgery addressed. The Journal offers its readers an interdisciplinary forum for clinical science and molecular research related to colorectal disease.
《国际结直肠疾病杂志》旨在发表新的和最先进的论文,研究涉及整个胃肠道的疾病的生理学和病理生理学。除了最初的研究文章,高科学质量的审查将包括和争议的问题,从快速发展的地区在胃肠外科解决。该杂志为读者提供了一个跨学科的论坛,为临床科学和分子研究与结直肠疾病有关。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
SURGERY (外科) 4区 GASTROENTEROLOGY & HEPATOLOGY (胃肠肝病学) 3区 |
57/80 62/200 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
237 | 217 | 20 |
引文计数(2018)
文献(2015-2017)
1436次引用
898篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Medicine
小类(学科):Gastroenterology
|
#66/128
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研究方向:直肠癌
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审稿时间: 6个月内
影响因子:5.315
ISSN:0148-396X
研究方向:医学-临床神经学
影响因子:1.725
ISSN:0028-3770
研究方向:医学-临床神经学
影响因子:2.21
ISSN:1878-8750
研究方向:CLINICAL NEUROLOGY-SURGERY
影响因子:4.332
ISSN:1092-0684
研究方向:CLINICAL NEUROLOGY-SURGERY
影响因子:2.816
ISSN:0001-6268
研究方向:医学-临床神经学
影响因子:2.8
ISSN:0344-5607
研究方向:医学-临床神经学
影响因子:0.972
ISSN:1019-5149
研究方向:医学-临床神经学
影响因子:1.532
ISSN:0256-7040
研究方向:医学-临床神经学
影响因子:1.165
ISSN:1016-2291
研究方向:医学-临床神经学
发表一篇学和医学成像类SCI论文
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INTERNATIONAL JOURNAL OF COLORECTAL DISEASE 投稿经验
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