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Abstract:
BACKGROUND & AIMS:HepaFat-Scan is a magnetic resonance imaging-based method for quantification of hepatic steatosis by volumetric liver fat fraction (VLFF) measurement. We aimed to validate VLFF and to compare it with controlled attenuation parameter (CAP) for determination of hepatic steatosis grade in patients with NAFLD, using histopathology and stereologic analyses of biopsies as the reference standard. METHODS:We performed a prospective study of consecutive adults with NAFLD who were scheduled for a liver biopsy at a tertiary hospital in Malaysia. Patients underwent VLFF and CAP measurements on the same day as their liver biopsy. Histopathology analyses of liver biopsy specimens were reported according to the Nonalcoholic Steatohepatitis Clinical Research Network scoring system. Stereologic analysis was performed using grid-point counting method combined with the Delesse principle. RESULTS:We analyzed data from 97 patients (mean age 57.0 ± 10.1 years; 44.33% male; 91.8% obese; 95.9% centrally obese). Based on histopathology analysis, the area under receiver operating characteristic curve (AUROC) for VLFF in detection of steatosis grade ≥S2 was 0.92 and for CAP the AUROC was 0.65 (P < .001). Based on stereological analysis, the AUROC for VLFF for detection of steatosis grade ≥S2 was 0.92 and for CAP the AUROC was 0.63, (P = .002); for identification of steatosis grade S3, the AUROC for VLFF was 0.92 and for CAP the AUROC was 0.68 (P < .001). CONCLUSIONS:In a prospective study of patients with NAFLD undergoing liver biopsy analysis, we found VLFF to more accurately determine grade of hepatic steatosis than CAP.
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最新影响因子:13.576 | 期刊ISSN:1542-3565 | CiteScore:3.75 |
出版周期:Monthly | 是否OA:YES | 出版年份:2003 |
期刊官方网址:http://www.journals.elsevier.com/clinical-gastroenterology-and-hepatology
自引率:5.50% | 研究方向:医学-胃肠肝病学 |
出版地区:UNITED STATES |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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Published by Elsevier Health. ISSN: 1542-3565. The mission of Clinical Gastroenterology and Hepatology (CGH) is to provide readers with a broad spectrum of themes in clinical gastroenterology and hepatology, including the diagnostic, endoscopic, interventional, and therapeutic advances in cancer, inflammatory diseases, functional gastrointestinal disorders, nutrition, absorption, and secretion. This peer-reviewed journal includes original articles as well as scholarly reviews, with the goal that all articles published will be immediately relevant to practice of the specialties of gastroenterology and hepatology. In addition to peer-reviewed articles, the journal includes invited key reviews and articles on endoscopy/practice-based technology, health-care policy, and practice management. Additionally, the journal''s Coding Corner offers professionals in GI practice answers to common coding and billing questions. Multimedia offerings include images, video abstracts, and podcasts. CGH also provides updates and commentary via Facebook, Twitter, LinkedIn, and its research blog The AGA Journals Blog. CGH is ranked 7th out of 78 journals in the Gastroenterology and Hepatology category on the 2015 Journal Citation Reports®, published by Thomson Reuters, and has an Impact Factor of 7.680. On average, authors receive decisions on their manuscripts in less than two weeks. CGH has an acceptance rate of 12% and is circulated to 20,300 individuals and institutions worldwide.
由爱思唯尔健康出版。ISSN: 1542 - 3565。 《临床胃肠病学与肝病》(CGH)的使命是为读者提供临床胃肠病学与肝病的广泛主题,包括癌症、炎症性疾病、功能性胃肠疾病、营养、吸收和分泌方面的诊断、内镜、介入和治疗进展。 这个同行评审的杂志包括原始文章和学术评论,目的是所有发表的文章将立即与胃肠病学和肝病学专业的实践相关。除了同行评审的文章外,该杂志还邀请了一些重要的评论和文章,内容涉及基于内镜/实践的技术、卫生保健政策和实践管理。此外,《华尔街日报》“s编码角落提供专业人士在胃肠道实践常见的编码和计费问题的答案。多媒体产品包括图像、视频摘要和播客。CGH还提供更新和评论通过Facebook、Twitter、LinkedIn、其研究博客博客AGA期刊。 CGH在汤森路透(Thomson Reuters) 2015年期刊引文报告(Citation Reports)®收录的78种胃肠病学和肝病类期刊中排名第七,影响因子为7.680。平均而言,作者在不到两周的时间内就能收到关于他们手稿的决定。CGH的录取率为12%,并在全球20,300个个人和机构中流通。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
GASTROENTEROLOGY & HEPATOLOGY(肠胃学和肝脏学) 2区 |
7/80 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
196 | 171 | 25 |
引文计数(2018)
文献(2015-2017)
5241次引用
1399篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Medicine
小类(学科):Hepatology
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#9/59
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2 |
大类(学科):Medicine
小类(学科):Gastroenterology
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#17/128
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研究方向:消化病 胃肠道
审稿时间: 3个月内
liting7111
研究方向:消化病 胃肠道
接受率: 非常困难(几乎不命中)
影响因子:2.566
ISSN:0739-7240
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影响因子:1.297
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影响因子:4.604
ISSN:1092-8529
研究方向:医学-精神病学
影响因子:5.345
ISSN:1398-5647
研究方向:医学-精神病学
影响因子:3.492
ISSN:1540-2002
研究方向:CLINICAL NEUROLOGY-PSYCHIATRY
影响因子:4.562
ISSN:0269-8811
研究方向:医学-精神病学
影响因子:6.533
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研究方向:医学-精神病学
影响因子:5.415
ISSN:0924-977X
研究方向:医学-精神病学
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