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Abstract:
BACKGROUND:A watch-and-wait strategy is a nonoperative alternative to sphincter-preserving surgery for patients with locally advanced rectal cancer who achieve a clinical complete response after neoadjuvant therapy. There are limited data about bowel function for patients undergoing this organ-preservation approach. OBJECTIVE:To compare bowel function in patients with rectal cancer managed with a watch-and-wait approach to bowel function in patients who underwent sphincter-preserving surgery (total mesorectal excision). DESIGN:Retrospective case-control study employing patient-reported outcomes. SETTING:Comprehensive cancer center. PATIENTS:Twenty-one patients underwent a watch-and-wait approach and were matched 1:1 with 21 patients from a pool of 190 patients who underwent sphincter-preserving surgery, based on age, gender, and tumor distance from the anal verge. MAIN OUTCOME MEASURES:Bowel function using the Memorial Sloan Kettering Cancer Center Bowel Function Instrument. RESULTS:Patients in the watch-and-wait arm had better bowel function on the overall scale (median total score, 76 vs 55; p < 0.001) and on all subscales, with the greatest difference on the urgency/soilage subscale (median score, 20 vs 12; p < 0.001). LIMITATIONS:Retrospective design, small sample size, and temporal variability between surgery and time of questionnaire completion. CONCLUSIONS:A watch-and-wait strategy correlated with overall better bowel function when compared to sphincter-preserving surgery using a comprehensive validated bowel dysfunction tool. See Video Abstract at http://links.lww.com/DCR/B218.
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最新影响因子:4.412 | 期刊ISSN:0012-3706 | CiteScore:2.57 |
出版周期:Monthly | 是否OA:YES | 出版年份:1958 |
期刊官方网址:http://link.springer.com/journal/10350
期刊投稿地址:https://www.springer.com/medicine/surgery/journal/10350
自引率:9.80% | 研究方向:医学-外科 |
出版地区:UNITED STATES |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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Diseases of the Colon and Rectum is published monthly for the American Society of Colon and Rectal Surgeons. It is designed for the publication of original papers that constitute significant contributions to the advancement of knowledge within the special field designated by the name of this journal. Discontinued in 2004.
《结肠直肠疾病》是美国结肠直肠外科学会出版的月刊。它旨在发布原始论文,这些论文对本期刊所指定的特殊领域内的知识进步做出了重大贡献。于2004年停产。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
GASTROENTEROLOGY & HEPATOLOGY (胃肠肝病学) 3区 SURGERY (外科) 2区 |
26/80 26/200 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
135 | 131 | 4 |
引文计数(2018)
文献(2015-2017)
1825次引用
711篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Medicine
小类(学科):Gastroenterology
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#34/128
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影响因子:13.029
ISSN:1522-8517
研究方向:医学-临床神经学
影响因子:4.506
ISSN:0167-594X
研究方向:医学-临床神经学
影响因子:7.723
ISSN:2162-402X
研究方向:ONCOLOGYIMMUNOLOGY-IMMUNOLOGY
影响因子:4.912
ISSN:1524-9557
研究方向:医学-免疫学
影响因子:12.02
ISSN:2326-6066
研究方向:ONCOLOGY-IMMUNOLOGY
影响因子:3.698
ISSN:1750-9378
研究方向:ONCOLOGY-IMMUNOLOGY
影响因子:6.63
ISSN:0340-7004
研究方向:医学-免疫学
影响因子:3.077
ISSN:1534-7354
研究方向:医学-全科医学与补充医学
影响因子:0
ISSN:1868-8497
研究方向:ONCOLOGY-ENDOCRINOLOGY & METABOLISM
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DISEASES OF THE COLON & RECTUM 投稿经验
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