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Abstract:
:The interneurons associated with rapid escape circuits are adapted for fast pathway activation and rapid conduction. An essential aspect of fast activation is the processing of sensory information with limited delays. Although aquatic annelid worms have some of the fastest escape responses in nature, the sensory networks that mediate their escape behavior are not well defined. Here, we demonstrate that the escape circuit of the mud worm, Lumbriculus variegatus, is a segmentally arranged network of sensory interneurons electrically coupled to the central medial giant fiber (MGF), the command-like interneuron for head withdrawal. Electrical stimulation of the body wall evoked fast, short-duration spikelets in the MGF, which we suggest are the product of intermediate giant fiber activation coupled to MGF collateral dendrites. Since these contact sites have immunoreactivity with a glutamate receptor antibody, and the glutamate receptor antagonist 6-cyano-7-nitroquinoxaline-2,3-dion abolishes evoked MGF responses, we conclude that the afferent pathway for MGF-mediated escape is glutamatergic. This electrically coupled sensory network may facilitate rapid escape activation by enhancing the amplitude of giant axon depolarization.
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最新影响因子:3.028 | 期刊ISSN:0021-9967 | CiteScore:3.3 |
出版周期:Weekly | 是否OA:YES | 出版年份:1911 |
期刊官方网址:http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1096-9861
自引率:11.80% | 研究方向:医学-动物学 |
出版地区:UNITED STATES |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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Established in 1891, JCN is the oldest continually published basic neuroscience journal. Historically, as the name suggests, the journal focused on a comparison among species to uncover the intricacies of how the brain functions. In modern times, this research is called systems neuroscience where animal models are used to mimic core cognitive processes with the ultimate goal of understanding neural circuits and connections that give rise to behavioral patterns and different neural states. Research published in JCN covers all species from invertebrates to humans, and the reports inform the readers about the function and organization of nervous systems in species with an emphasis on the way that species adaptations inform about the function or organization of the nervous systems, rather than on their evolution per se. JCN publishes primary research articles and critical commentaries and review-type articles offering expert insight in to cutting edge research in the field of systems neuroscience; a complete list of contribution types is given in the Author Guidelines. For primary research contributions, only full-length investigative reports are desired; the journal does not accept short communications.
JCN成立于1891年,是最古老的连续出版的基础神经科学杂志。从历史上看,正如它的名字所暗示的那样,该杂志关注的是物种之间的比较,以揭示大脑功能的复杂性。在现代,这项研究被称为系统神经科学,动物模型被用来模拟核心的认知过程,最终目的是理解导致行为模式和不同神经状态的神经回路和连接。 研究发表在JCN涵盖所有物种从无脊椎动物到人类,和报告告知读者在物种的神经系统的功能和组织强调物种适应性的方式通知的功能或神经系统的组织,而不是在他们的进化本身。 JCN发表主要的研究论文、评论和评论类文章,为系统神经科学领域的前沿研究提供专家见解;在作者指南中给出了一个完整的贡献类型列表。对于主要的研究贡献,只需要完整的调查报告;期刊不接受短讯。
大类(学科) | 小类(学科) | 学科排名 |
生物 |
ZOOLOGY (动物学) 3区 NEUROSCIENCES (神经科学) 1区 |
103/261 6/167 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
205 | 197 | 8 |
引文计数(2018)
文献(2015-2017)
1881次引用
570篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Neuroscience
小类(学科):General Neuroscience
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#31/111
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研究方向:比较神经生物学
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研究方向:比较神经科学
审稿时间: 3个月内 接受率: 中等(50%命中)
影响因子:5.315
ISSN:0148-396X
研究方向:医学-临床神经学
影响因子:1.725
ISSN:0028-3770
研究方向:医学-临床神经学
影响因子:2.21
ISSN:1878-8750
研究方向:CLINICAL NEUROLOGY-SURGERY
影响因子:4.332
ISSN:1092-0684
研究方向:CLINICAL NEUROLOGY-SURGERY
影响因子:2.816
ISSN:0001-6268
研究方向:医学-临床神经学
影响因子:2.8
ISSN:0344-5607
研究方向:医学-临床神经学
影响因子:0.972
ISSN:1019-5149
研究方向:医学-临床神经学
影响因子:1.532
ISSN:0256-7040
研究方向:医学-临床神经学
影响因子:1.165
ISSN:1016-2291
研究方向:医学-临床神经学
发表一篇学和医学成像类SCI论文
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