Objectively-Measured Activity Patterns are Associated with Home Blood Pressure in Memory Clinic Patients.

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Abstract:

BACKGROUND:Physicians are cautious to prescribe antihypertensive drugs in frail older adults because of the potential adverse effects, especially in those with cognitive complaints. Lifestyle aspects might provide safe targets to lower blood pressure in older adults. OBJECTIVE:Our goal was to evaluate the associations between activity patterns and blood pressure in memory clinic patients. METHODS:We used an observational cross-sectional study to measure activity patterns with the ActivPAL accelerometer, and simultaneous home blood pressure levels in memory clinic patients (age range 51-87 years old). Office blood pressure was assessed during routine clinical practice. RESULTS:41 patients (mean age of 74.3 (7.7) years of age, 46% female) were included. Sedentary parameters were associated with higher mean home blood pressure, with the strongest correlation between more prolonged sitting bouts and higher SBP (r = 0.58, p < .0001). Physical activity parameters were negatively associated with mean home blood pressure. Adjusted regression estimates remained significant, showing, e.g., a 4.5 (95% CI = 1.6;7.4) mmHg increase in SBP for every hour of sitting per day and a -1.0 (95% CI = -1.8;-0.2) mmHg decrease in DBP for every additional 1000 steps per day. No strong correlations were found between any of the activity pattern variables and office blood pressure. CONCLUSION:Associations between activity pattern variables and blood pressure were only found with home blood pressure measurements, not with office measurements. Longitudinal evaluations of these associations are now needed to explore if reducing prolonged sedentary bouts and increasing step count indeed serve as safe targets to lower blood pressure.

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JOURNAL OF ALZHEIMERS DISEASE

J ALZHEIMERS DIS
最新影响因子:4.16 期刊ISSN:1387-2877 CiteScore:
出版周期:Semimonthly 是否OA:YES 出版年份:1998

期刊官方网址:http://www.j-alz.com/

期刊投稿地址:http://www.j-alz.com/submit

自引率:11.70% 研究方向:医学-神经科学
出版地区:NETHERLANDS

SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)

NCBI查询:PubMed Central (PMC)链接全文检索(pubmed central)

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JOURNAL OF ALZHEIMERS DISEASE 期刊简介

英文简介:

Published by IOS Press. ISSN: 1387-2877. The Journal of Alzheimer's Disease is an international multidisciplinary journal to facilitate progress in understanding the etiology, pathogenesis, epidemiology, genetics, behavior, treatment and psychology of Alzheimer's disease. The journal publishes research reports, reviews, short communications, book reviews, and letters-to-the-editor. The journal is dedicated to providing an open forum for original research that will expedite our fundamental understanding of Alzheimer's disease.

中文简介:(来自Google、百度翻译)

由IOS出版社出版。ISSN: 1387 - 2877。 《阿尔茨海默病杂志》是一份国际性的多学科期刊,旨在促进对阿尔茨海默病的病因、发病机制、流行病学、遗传学、行为、治疗和心理学的理解。该杂志出版研究报告、评论、简短的交流、书评和给编辑的信件。该杂志致力于为原始研究提供一个开放的论坛,将加快我们对阿尔茨海默病的基本认识。

JOURNAL OF ALZHEIMERS DISEASE 期刊中科院评价数据

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大类(学科) 小类(学科) 学科排名
医学 NEUROSCIENCES(神经系统科学) 3区
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最新公布的期刊年发文量

年度总发文量 年度论文发表量 年度综述发表量
736 660 76
总被引频次:20383
特征因子:0.041470

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JOURNAL OF ALZHEIMERS DISEASE 期刊CiteScore评价数据

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SCLmago期刊等级衡量经过加权后的期刊受引用次数,引用次数的加权值由施引期刊的学科领域和声望(SJR)决定。
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每篇文章中来源出版物的标准化影响将实际受引用情况对照期刊所属学科领域中预期的受引用情况进行衡量。

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(由下方点评分析获得,2人参与,17647人阅读)

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  • avatar

    liting7111

    研究方向:阿尔兹海默症 病理

    接受率: 比较困难(25%命中)

    审稿速度块,一审一个月就回来了,意见也很中肯,二审修回三天就接收,pubmed上也能很快的搜索到。
    2020-01-28
  • avatar

    liting7111

    研究方向:神经生物学

    接受率: 比较困难(25%命中)

    阿尔兹海默病方向,审稿很快,一个月不到就给了审稿结果,大修修回就接收了。审稿人给的建议相当中肯,杂志效率也很高,推荐大家投稿。
    2019-06-22

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