发表一篇学和医学成像类SCI论文
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Abstract:
Background: Anorexia nervosa (AN) is a debilitating illness whose neural basis remains unclear. Studies using tract-based spatial statistics (TBSS) with diffusion tensor imaging (DTI) have demonstrated differences in white matter (WM) microarchitecture in AN, but the findings are inconclusive and controversial.Objectives: To identify the most consistent WM abnormalities among previous TBSS studies of differences in WM microarchitecture in AN.Methods: By systematically searching online databases, a total of 11 datasets were identified, including 245 patients with AN and 246 healthy controls (HC). We used Seed-based d Mapping to analyze fractional anisotropy (FA) differences between AN patients and HC, and performed meta-regression analysis to explore the effects of clinical characteristics on WM abnormalities in AN.Results: The pooled results of all AN patients showed robustly lower FA in the corpus callosum (CC) and the cingulum compared to HC. These two regions preserved significance in the sensitivity analysis as well as in all subgroup analyses. Fiber tracking showed that the WM tracts primarily involved were the body of the CC and the cingulum bundle. Meta-regression analysis revealed that the body mass index and mean age were not linearly correlated with the lower FA.Conclusions: The most consistent WM microstructural differences in AN were in the interhemispheric connections and limbic association fibers. These common “targets” advance our understanding of the complex neural mechanisms underlying the puzzling symptoms of AN, and may help in developing early treatment approaches.
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最新影响因子:5.152 | 期刊ISSN:1662-453X | CiteScore:3.94 |
出版周期: | 是否OA:YES | 出版年份:0 |
期刊官方网址:http://journal.frontiersin.org/journal/neuroscience
期刊投稿地址:http://www.frontiersin.org/submission/submissioninfo.aspx
自引率:4.70% | 研究方向:NEUROSCIENCES- |
出版地区:SWITZERLAND |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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Frontiers in Neuroscience is a leading journal in its field, publishing rigorously peer-reviewed research across a wide spectrum of specialties and disciplines. Field Chief Editor Idan Segev at the Hebrew University of Jerusalem is supported by an outstanding Editorial Board of international researchers. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide. These are historical times for brain research - namely for the Brain itself. The convergence of novel molecular and optical techniques paves the way to the era of "causation neuroscience," whereby many thousands of cells composing the system studied can be recorded from and manipulated in a very specific manner (e.g. via "optogenetics") and the behavioral and functional consequences of these manipulations explored in vivo. It is also a new era of "anatomical neuroscience" - as recently developed techniques, both at the whole-brain level ("connectome") and the local circuit and synaptic level ("connectomics") become more widely used. These approaches allow us to link structure of specific brain regions and local circuits to function more astutely. New research fields have recently emerged, e.g. "neuroeconomics" and "neuroenergetics." In addition, and critically, in our information-generating world, new informatics-based methods are being developed to store the enormous amount of new “big data” in a systematic manner, for data-preservation, data-mining and for extracting key information from these data. And, importantly, theoretical and computational approaches are being developed for integrating this diverse data and for deriving principles of brain operations that may otherwise lie hidden within the intricacies of brain circuits. As the field is growing fast, we seek to integrate and cross-link studies and citations in related subfields, providing an overview of the state-of-the-art in these fields and the ways in which they complement each other. After all, we may each of us look at the brain from particular standpoints - all the way from "genes to behavior" - yet the brain integrates all these levels seamlessly; this journal should reflect this in the best possible way.
《神经科学前沿》是该领域的领军期刊,发表了广泛的专业和学科的同行评审研究。耶路撒冷希伯来大学的现场总编辑伊丹·塞格夫得到了一个杰出的国际研究人员编辑委员会的支持。这本多学科开放获取期刊是向研究人员、学者、临床医生和全世界公众传播和交流科学知识和有影响力的发现的前沿。 这是大脑研究的历史时期——也就是大脑本身。新的分子和光学技术的融合为“因果神经科学”的时代铺平了道路,在这一时代,构成所研究系统的数千个细胞可以以一种非常特殊的方式(例如通过“光遗传学”)进行记录和操作,以及这些操作在体内的行为和功能后果。这也是一个“解剖神经科学”的新时代——正如最近发展的技术,无论是在整个大脑层面(“连接体”),局部回路和突触层面(“连接体”)都得到了更广泛的应用。这些方法使我们能够将特定大脑区域的结构和局部电路联系起来,从而更加敏锐地发挥作用。最近出现了新的研究领域,如“神经经济学”和“神经能量学”。此外,而且,至关重要的是,在我们的信息生成世界中,正在开发基于信息学的新方法,以系统地存储大量新的“大数据”,用于数据保存、数据挖掘和提取关键信息。从这些数据中。而且,重要的是,理论和计算方法正在开发中,以整合这些不同的数据,并推导出可能隐藏在错综复杂的大脑回路中的大脑操作原理。 随着该领域的快速发展,我们试图整合和交叉链接相关子领域的研究和引文,概述这些领域的最新技术及其相互补充的方式。毕竟,我们每个人都可能从特定的角度看待大脑——从“基因”到行为——然而大脑无缝地整合了所有这些层面;这本杂志应该以最好的方式反映这一点。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
NEUROSCIENCES (神经科学) 3区 |
77/261 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
706 | 590 | 116 |
引文计数(2018)
文献(2015-2017)
6150次引用
1559篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Neuroscience
小类(学科):General Neuroscience
|
#20/111
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研究方向:医药科学 神经系统 精神疾病 神经免疫调节异常 神经免疫相关疾病
审稿时间: 3个月内
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研究方向:神经母细胞瘤 激素
接受率: 一般容易(75%命中)
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研究方向:医学 神经科学
审稿时间: 2个月内
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接受率: 中等(50%命中)
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研究方向:医药科学 康复医学
审稿时间: 3个月内
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研究方向:医药科学 影像医学 生物医学工程 fMRI与脑、脊髓功能异常检测
审稿时间: 3个月内
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研究方向:神经退行性疾病 神经免疫
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研究方向:工程技术 神经科学
审稿时间: 8个月内
影响因子:5.576
ISSN:0885-3924
研究方向:医学-临床神经学
影响因子:6.005
ISSN:0192-415X
研究方向:医学-全科医学与补充医学
影响因子:202.731
ISSN:0140-6736
研究方向:医学-医学:内科
影响因子:2.898
ISSN:1807-5932
研究方向:医学-医学:内科
影响因子:1.817
ISSN:0025-7974
研究方向:医学-医学:内科
影响因子:3.006
ISSN:2044-6055
研究方向:MEDICINE, GENERAL & INTERNAL-
影响因子:0.834
ISSN:0020-9554
研究方向:医学-医学:内科
影响因子:0.522
ISSN:1108-4189
研究方向:MEDICINE, GENERAL & INTERNAL-
影响因子:11.15
ISSN:1741-7015
研究方向:医学-医学:内科
发表一篇学和医学成像类SCI论文
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