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Abstract:
:Trace amines have been reported to be neuromodulators of monoaminergic systems. Trace amines receptor 5 (TAAR5) is expressed in several regions of mice central nervous system, such as amygdala, arcuate nucleus and ventromedial hypothalamus, but very limited information is available on its functional role. The purpose of this study is to examine the effect of TAAR5 agonist alpha-NETA on the generation of mismatch negativity (MMN) analogue in C57BL/6 mice. Event-related potentials have been recorded from awake mice in oddball paradigms before and after the alpha-NETA administration. Alpha-NETA has been found to decrease N40 MMN-like difference, which resulted from the increased response to standard stimuli. An opposite effect has been found for the P80 component: the amplitude increased in response both to standard and deviant stimuli. A significant increase in N40 peak latency after the alpha-NETA administration has been found. This may suggest a reduced speed of information processing similar to the increase in P50 and N100 components latencies in schizophrenia patients. These results provide new evidence for a role of TAAR5 in cognitive processes.
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最新影响因子:3.715 | 期刊ISSN:0361-9230 | CiteScore:3.32 |
出版周期:Semimonthly | 是否OA:YES | 出版年份:1976 |
期刊官方网址:http://www.journals.elsevier.com/brain-research-bulletin/
期刊投稿地址:http://ees.elsevier.com/brb/default.asp?acw=d571d4cb7d6e5513072fb22
自引率:8.00% | 研究方向:医学-神经科学 |
出版地区:UNITED STATES |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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Brain Research Bulletin is dedicated to the rapid publication of significant research articles and reviews in all areas of the neurosciences. In addition to reports of original research, the journal also publishes general and speculative reviews, topical debates, methodological developments, theoretical articles and occasional special issues. The editors are committed to maintaining a high quality of all published reports and to a rapid and fair review process. Manuscripts will be subject to a process of anonymous review (the names of authors and their affiliations will be disclosed to the referees only when the review process is complete). Accelerated publication is the goal for all manuscripts. Articles will be published in English. To link to the editorial office homepage: http://www.brb.cf.ac.uk
《大脑研究公报》致力于神经科学各个领域的重要研究文章和评论的快速出版。除了原创研究报告,该杂志还发表一般性和思辨性评论、专题辩论、方法论发展、理论文章和偶尔的特刊。编辑们致力于保持所有出版报告的高质量和快速公正的审查过程。稿件将接受匿名评审(只有在评审过程结束后,作者姓名及其所属单位才会向评审人员披露)。加快出版是所有稿件的目标。文章将以英文发表。编辑部网页:http://www.brb.cf.ac.uk
大类(学科) | 小类(学科) | 学科排名 |
医学 |
NEUROSCIENCES (神经科学) 3区 |
99/261 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
182 | 161 | 21 |
引文计数(2018)
文献(2015-2017)
1357次引用
409篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Neuroscience
小类(学科):General Neuroscience
|
#28/111
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研究方向:神经科学
审稿时间: 3个月内 接受率: 一般容易(75%命中)
影响因子:3.532
ISSN:1541-6933
研究方向:医学-临床神经学
影响因子:19.334
ISSN:1466-609X
研究方向:医学-危重病医学
影响因子:2.799
ISSN:0210-5691
研究方向:CRITICAL CARE MEDICINE-
影响因子:3.879
ISSN:0749-0704
研究方向:医学-危重病医学
影响因子:9.296
ISSN:0090-3493
研究方向:医学-危重病医学
影响因子:41.787
ISSN:0342-4642
研究方向:医学-危重病医学
影响因子:4.298
ISSN:0883-9441
研究方向:医学-危重病医学
影响因子:10.318
ISSN:2110-5820
研究方向:CRITICAL CARE MEDICINE-
影响因子:5.692
ISSN:1441-2772
研究方向:CRITICAL CARE MEDICINE-
发表一篇学和医学成像类SCI论文
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