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Abstract:
PRECIS:In a cohort study of 120,307 participants with 25+ years of follow-up, a history of non-melanoma skin cancer was associated with a 40% higher exfoliation glaucoma risk. PURPOSE:To evaluate the relationship between non-melanoma skin cancer (a marker of ultraviolet radiation exposure) and exfoliation glaucoma (XFG). METHODS:We performed a cohort study of US women (n=79,102; 1980-2014) and men (n=41,205; 1986-2014), aged 40+ years and at risk for glaucoma who reported eye exams. From 1984 (women)/1988 (men), we asked about basal cell carcinoma (BCC) or squamous cell carcinoma (SCC) history separately; in prior years, we asked about any non-melanoma skin cancer history in a single question. SCC was confirmed with histopathology reports while BCC and any early (<1984/<1988) non-melanoma skin cancer history was self-reported. Incident XFG cases (362 women and 83 men) were confirmed with medical records. Using pooled data, we estimated multivariable-adjusted relative risks (MVRR; 95% confidence intervals [CIs]) with Cox proportional hazards models that were stratified by age (in months), 2-year time period at risk and average lifetime residential latitude. RESULTS:In multivariable-adjusted analyses, we observed a 40% higher XFG risk with any non-melanoma skin cancer history (MVRR=1.40; 95% CI=1.08,1.82); the association was observed even with 4 and 8 year lags in non-melanoma skin cancer history. Also, the non-melanoma skin cancer association was stronger in younger (<65▒y; MVRR=2.56; 95% CI=1.62,4.05) versus older participants (≥65▒y; MVRR=1.25; 95% CI=0.94,1.66; p for interaction=0.01) and those living in northern latitudes (≥42° north; MVRR=1.92; 95% CI=1.28,2.88) versus more southern latitudes (<42° north; MVRR=1.19; 95% CI=0.86,1.66; p for interaction=0.04). CONCLUSIONS:Non-melanoma skin cancer was associated with higher XFG risk, particularly among younger participants and those living in Northern US.
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最新影响因子:2.29 | 期刊ISSN:1057-0829 | CiteScore:1.82 |
出版周期:Monthly | 是否OA:YES | 出版年份:1992 |
期刊官方网址:http://journals.lww.com/glaucomajournal/pages/default.aspx
自引率:17.70% | 研究方向:医学-眼科学 |
出版地区:UNITED STATES |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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Journal of Glaucoma provides a stimulating forum for discussion of clinical, scientific, and socioeconomic issues of greatest concern to clinicians who care for glaucoma patients. Each issue presents original articles on new approaches to diagnosis, innovations in pharmacological therapy and surgical technique, and basic science advances that impact on clinical practice.
青光眼杂志提供了一个激动人心的论坛,用于讨论临床医生最关心的临床,科学和社会经济问题,这些问题是关心青光眼患者的。每期都会提供有关诊断新方法,药物治疗和手术技术创新以及影响临床实践的基础科学进展的原创文章。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
OPHTHALMOLOGY (眼科学) 4区 |
37/59 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
246 | 241 | 5 |
引文计数(2018)
文献(2015-2017)
1205次引用
662篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Medicine
小类(学科):Ophthalmology
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#33/108
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影响因子:0.753
ISSN:0534-0012
研究方向:AGRONOMY-GENETICS & HEREDITY
影响因子:1.282
ISSN:0037-5349
研究方向:农林科学-林学
影响因子:3.017
ISSN:1364-6745
研究方向:医学-临床神经学
影响因子:3.469
ISSN:1475-2875
研究方向:医学-寄生虫学
影响因子:0.735
ISSN:0972-9062
研究方向:INFECTIOUS DISEASES-PARASITOLOGY
影响因子:0.209
ISSN:0125-1562
研究方向:PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-INFECT
影响因子:1.794
ISSN:0142-6338
研究方向:医学-热带医学
影响因子:0.828
ISSN:0049-4755
研究方向:医学-公共卫生、环境卫生与职业卫生
影响因子:3.918
ISSN:1360-2276
研究方向:医学-公共卫生、环境卫生与职业卫生
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