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发表一篇学和医学成像类SCI论文
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Abstract:
:Objectives: To evaluate cancer-specific (CSS) and overall survival (OS) in a group of frail patients who were treated with RT without chemotherapy and to compare them with a matched cohort of patients treated with RC.Methods: This study identified 71 patients treated with RT only for high-risk bladder cancer. Patients with metastatic (cN + or cM+) or non-resectable tumors (cT4) and those who received any form of chemotherapy were excluded. Patients where matched 1:1 using propensity scores which adjusted for the effects of age, clinical stage and age-adjusted Charlson comorbidity index (CCI). OS and CSS were evaluated using the Cox proportional hazards regression model and the Fine and Gray competing risk model.Results: In the overall population, RT was associated with worse OS (HR = 1.78, 95% CI = 1.15-2.77, p = 0.01) compared to RC, but not with CSS (HR 1.1, p = 0.74). In the matched cohort, RT was neither associated with OS nor CSS (p > 0.05) compared to RC. In the competing risk analyses no statistically significant association of any of the treatments was observed in the total or in the matched data set (p > 0.05).Conclusion: The use of RT may be an alternative option in well selected patients with limited disease who are considered unfit for systemic chemotherapy and RC. Future research should focus on improving patient selection and assess the quality-of-life as well as the need for reintervention in patients treated with RT.
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最新影响因子:1.899 | 期刊ISSN:2168-1805 | CiteScore:1.53 |
出版周期: | 是否OA:YES | 出版年份:0 |
自引率:8.70% | 研究方向:UROLOGY & NEPHROLOGY- |
出版地区:SWEDEN |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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Scandinavian Journal of Urology is a journal for clinical urologists and publishes papers within all fields of clinical urology, with experimental papers related to clinical questions also invited. Important reports with great news value are published promptly. The journal presents a wide range of topics such as: Prostatic diseases Incontinence Nocturnal enuresis Kidney diseases
《斯堪的纳维亚泌尿学杂志》是一份临床泌尿学杂志,发表临床泌尿学各领域的论文,同时也邀请与临床问题相关的实验论文。具有重大新闻价值的重要报道及时发布。 该杂志提出了广泛的主题,如: 前列腺疾病 尿失禁 夜尿症 肾脏疾病
大类(学科) | 小类(学科) | 学科排名 |
医学 |
UROLOGY & NEPHROLOGY (泌尿学与肾脏学) 4区 |
52/76 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
76 | 70 | 6 |
引文计数(2018)
文献(2015-2017)
384次引用
251篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Medicine
小类(学科):Nephrology
|
#29/59
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2 |
大类(学科):Medicine
小类(学科):Urology
|
#42/97
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