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Abstract:
OBJECTIVE:To examine the effect of non-muscle-invasive bladder cancer (NMIBC) diagnosis and treatment on survivors' quality of life (QoL). PATIENTS AND METHODS:Of the 5979 patients with NMIBC diagnosed between 2010 and 2014 in North Carolina, 2000 patients were randomly selected to be invited to enroll in this cross-sectional study. Data were collected by postal mail survey. The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Core (QLQ-C30) and the NMIBC-specific module were included in the survey to measure QoL. Descriptive statistics, t-tests, anova, and Pearson's correlation were used to describe demographics and to assess how QoL varied by sex, cancer stage, time since diagnosis, and treatment. RESULTS:A total of 398 survivors returned questionnaires (response rate: 23.6%). The mean QoL score for QLQ-C30 (range 0-100, higher = better QoL in all domains but symptoms) for global health status was 73.6, function domain scores ranged from 83.9 to 86.5, and scores for the top five symptoms (insomnia, fatigue, dyspnoea, pain, and financial difficulties) ranged from 14.1 to 24.3. The lowest NMIBC-specific QoL domain was sexual issues including sexual function, enjoyment, problems, and intimacy. Women had worse bowel problems, sexual function, and sexual enjoyment than men but better sexual intimacy and fewer concerns about contaminating their partner. Stage Ta had the highest global health status, followed by T1 and Tis. QoL did not vary by time since diagnosis except for sexual function. The cystectomy group (n = 21) had worse QoL in sexual function, discomfort with sexual intimacy, sexual enjoyment, and male sexual problems than the non-cystectomy group (n = 336). CONCLUSION:Survivors of NMIBC face a unique burden associated with their diagnosis and the often-lifelong surveillance and treatment regimens. The finding has important implications for the design of tailored supportive care interventions to improve QoL for NMIBC survivors.
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最新影响因子:5.969 | 期刊ISSN:1464-4096 | CiteScore:3.37 |
出版周期:Semimonthly | 是否OA:YES | 出版年份:1999 |
自引率:7.70% | 研究方向:医学-泌尿学与肾脏学 |
出版地区:ENGLAND |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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The Journal of the British Association of Urological Surgeons, the European Society of Paediatric Urology and the Societe Internationale d'Urologie BJU International is one of the most highly respected medical journals in the world. It presents unparalleled coverage of contemporary urological opinion, clinical reports and studies, innovations and developments.
《国际现代泌尿外科杂志》、《英国泌尿外科医师协会杂志》和《欧洲儿科泌尿学学会》是世界上最受尊敬的医学期刊之一。它提供了无与伦比的现代泌尿学观点,临床报告和研究,创新和发展的报道。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
UROLOGY & NEPHROLOGY (泌尿学与肾脏学) 2区 |
9/76 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
236 | 221 | 15 |
引文计数(2018)
文献(2015-2017)
3860次引用
1146篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Medicine
小类(学科):Urology
|
#5/97
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研究方向:泌尿外科 组织工程 膀胱修复
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研究方向:医药科学 泌尿系统 肾脏物质转运异常
审稿时间: 3个月内
影响因子:5.315
ISSN:0148-396X
研究方向:医学-临床神经学
影响因子:1.725
ISSN:0028-3770
研究方向:医学-临床神经学
影响因子:2.21
ISSN:1878-8750
研究方向:CLINICAL NEUROLOGY-SURGERY
影响因子:4.332
ISSN:1092-0684
研究方向:CLINICAL NEUROLOGY-SURGERY
影响因子:2.816
ISSN:0001-6268
研究方向:医学-临床神经学
影响因子:2.8
ISSN:0344-5607
研究方向:医学-临床神经学
影响因子:0.972
ISSN:1019-5149
研究方向:医学-临床神经学
影响因子:1.532
ISSN:0256-7040
研究方向:医学-临床神经学
影响因子:1.165
ISSN:1016-2291
研究方向:医学-临床神经学
发表一篇学和医学成像类SCI论文
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